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In-vitro Mutagenesis01:16

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To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
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In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing
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Author Correction: Universal toxin-based selection for precise genome engineering in human cells

Songyuan Li1, Nina Akrap2, Silvia Cerboni3

  • 1Translational Genomics, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden. songyuan.li@astrazeneca.com.

Nature Communications
|May 11, 2021
PubMed
Summary

No abstract available in PubMed .

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