Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A Hydrogel Strategy to Augment Tissue Adenosine to Improve Hindlimb Perfusion.

Arteriosclerosis, thrombosis, and vascular biology·2021

Same author

Critical Limb Ischemia Induces Remodeling of Skeletal Muscle Motor Unit, Myonuclear-, and Mitochondrial-Domains.

Scientific reports·2019

Same author

The small heat shock protein HSPB1 protects mice from sepsis.

Scientific reports·2018

Same author

The receptor for advanced glycation end products impairs collateral formation in both diabetic and non-diabetic mice.

Laboratory investigation; a journal of technical methods and pathology·2016

Search research articles

Related Experiment Video

Updated: Nov 6, 2025

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

Optimization of Oxygen Delivery Within Hydrogels.

Sophia M Mavris¹, Laura M Hansen²

¹The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 313 Ferst Drive, Atlanta, GA 30332.

Journal of Biomechanical Engineering

|May 11, 2021

Summary

This summary is machine-generated.

Tissue engineering faces oxygen delivery challenges in hydrogel constructs. Recent innovations in oxygen transport modeling, sensing, and delivery are crucial for clinical translation of tissue-engineered products.

More Related Videos

Fabrication and Operation of an Oxygen Insert for Adherent Cellular Cultures

Fabrication and Operation of an Oxygen Insert for Adherent Cellular Cultures

Published on: January 6, 2010

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

Related Experiment Videos

Last Updated: Nov 6, 2025

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components

Published on: July 18, 2018

Fabrication and Operation of an Oxygen Insert for Adherent Cellular Cultures

Fabrication and Operation of an Oxygen Insert for Adherent Cellular Cultures

Published on: January 6, 2010

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

Area of Science:

Biomaterials Science
Tissue Engineering
Biomedical Engineering

Background:

Tissue engineering has advanced significantly over 30 years, with new biomaterials and cell sources.
Clinical translation remains limited by challenges, notably insufficient oxygen availability in engineered tissues.
Oxygen insufficiency hinders nutrient delivery, impacting the viability and function of engineered constructs.

Purpose of the Study:

To review recent advancements in oxygen transport within hydrogel-based tissue engineering.
To compare current research on modeling, sensing, and optimizing oxygen in hydrogels.
To highlight innovations addressing diffusion-limited oxygen delivery.

Main Methods:

Literature review of recent research on oxygen transport in hydrogels.
Comparative analysis of modeling, sensing, and optimization techniques.
Identification of novel technologies for enhanced oxygen delivery.

Main Results:

Oxygen availability is a critical bottleneck for clinical translation in tissue engineering.
Advanced modeling and sensing techniques are improving oxygen management in hydrogels.
New technologies offer solutions beyond traditional diffusion for oxygen transport.

Conclusions:

Overcoming oxygen limitations is key to advancing hydrogel-based tissue engineering.
Innovations in oxygen transport are essential for future clinical applications.
This review provides insights into optimizing oxygen delivery for better tissue-engineered constructs.