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Augmenting Transfer Learning with Feature Extraction Techniques for Limited Breast Imaging Datasets.

Aswiga R V1, Aishwarya R2, Shanthi A P2

  • 1Department of Computer Science and Engineering, Amrita School of Engineering, Amrita Vishwa Vidyapeetham, Chennai, Tamil Nadu, India. aswiga91@gmail.com.

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This study introduces a novel two-level transfer learning framework for classifying digital breast tomosynthesis (DBT) images. The approach effectively utilizes knowledge from non-medical and mammography datasets to improve DBT image classification accuracy, even with limited data.

Keywords:
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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Machine Learning

Background:

  • Computer-aided detection (CADe) and diagnosis (CADx) systems are crucial for medical image classification.
  • Mammography-based CAD systems face limitations, especially with dense breasts, due to data availability and detection accuracy issues.
  • Digital breast tomosynthesis (DBT) offers improved imaging but suffers from scarce publicly available datasets.

Purpose of the Study:

  • To develop a two-level transfer learning framework for classifying digital breast tomosynthesis (DBT) datasets.
  • To leverage knowledge from readily available non-medical and mammography datasets to enhance DBT image classification.
  • To improve the accuracy and efficiency of CAD systems for breast cancer detection using DBT.

Main Methods:

  • Proposed a multilevel transfer learning (MLTL) framework to transfer knowledge from general non-medical and mammography datasets to the target DBT dataset.
  • Introduced a feature extraction based transfer learning (FETL) framework to further enhance the MLTL framework's performance.
  • Evaluated three different feature extraction techniques within the FETL framework to optimize classification.

Main Results:

  • Achieved an area under the receiver operating characteristic (ROC) curve of 0.89.
  • Demonstrated high classification performance using a small percentage of source (2.08% non-medical), intermediate (5.09% mammography), and target (3.94% DBT) datasets.
  • The proposed FETL framework significantly improved upon the basic MLTL framework's classification performance.

Conclusions:

  • The developed two-level transfer learning framework effectively classifies DBT datasets, addressing data scarcity issues.
  • Transfer learning offers a viable solution for improving CAD systems in medical imaging, particularly for newer modalities like DBT.
  • The study highlights the potential of combining MLTL and FETL for robust medical image analysis and diagnosis.