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Updated: Nov 6, 2025

Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling
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[Identification techniques of small molecule drug target proteins without chemical modification and its applications:

Jie Ma1, Qiang Liu1

  • 1Department of Histoembryology, Genetics and Developmental Biology, Basic Medical College, Shanghai Key Laboratory of Reproductive Medicine, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.

Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology
|May 11, 2021
PubMed

Keywords:
cellular thermal shift assaydrug affinity responsive target stabilitylabel-freesmall molecule drugsstability of proteins from rates of oxidationthermal proteome profiling

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