Related Experiment Video
Updated: Nov 6, 2025

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Published on: August 1, 2019
Guided Internet-Based Cognitive Behavioral Therapy for Depression: Implementation Cost-Effectiveness Study
Jordi Piera-Jiménez1,2,3, Anne Etzelmueller4, Spyros Kolovos5
1Open Evidence Research Group, Universitat Oberta de Catalunya, Barcelona, Spain.
Internet-based cognitive behavioral therapy (iCBT) for major depressive disorder, like the Super@ program, is more expensive than usual care but proves cost-effective in Spain. This approach offers a viable treatment option within the established willingness-to-pay threshold.
Area of Science:
- Mental Health
- Health Economics
- Digital Health
Background:
- Major depressive disorder (MDD) is a chronic condition with increasing prevalence in aging populations.
- Internet-based cognitive behavioral therapy (iCBT) demonstrates proven efficacy in treating MDD.
Purpose of the Study:
- To assess the cost-effectiveness of the Super@ program, a community internet-based cognitive behavioral therapy intervention for MDD in Spain.
- Evaluate the Super@ program against usual care from both healthcare and societal perspectives.
Main Methods:
- A 3-state Markov model was employed using the MAFEIP tool to evaluate cost-effectiveness.
- Data on costs and effectiveness were prospectively collected for the Super@ program and from literature for usual care.
- Patient Health Questionnaire-9 (PHQ-9) scores were used to determine health states, transition probabilities, and utilities.
Main Results:
- The Super@ intervention was more costly than usual care, with incremental cost-effectiveness ratios (ICERs) of €29,367 (discounted) and €26,484 (nondiscounted) per quality-adjusted life-year (QALY).
- The intervention was deemed cost-effective, falling within Spain's €30,000 willingness-to-pay (WTP) threshold per QALY.
- Sensitivity analyses indicated that cost reductions through scale-up could lower the ICER, but exceeding the WTP threshold was possible with a 5% discount in incremental effects.
Conclusions:
- The Super@ internet-based cognitive behavioral therapy program for MDD is more expensive than usual care.
- Despite higher costs, the Super@ program's implementation in Spain is considered cost-effective based on the €30,000 WTP threshold.
- This digital mental health intervention presents a valuable option for treating major depressive disorder within the Spanish healthcare and societal context.
Related Concept Videos
Cognitive Therapy
Rational Emotive Behavior Therapy
Electroconvulsive Therapy
Treatment Strategies for Psychological Disorders
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
Beck's Cognitive Therapy
Arbitrary Inference
Arbitrary inference involves making conclusions without sufficient...
The Placebo Effect

