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Changes in renal function following delivery of the lamb by caesarean section
1School of Physiology and Pharmacology, University of New South Wales, Sydney, Australia.
Six lambs were delivered by caesarean section at 139 to 145 days of gestation. Birth was associated with a rise in glomerular filtration rate from 4.81 +/- 0.62 to 5.90 +/- 0.74 ml/min and a transient natriuresis secondary to a fall in fractional sodium reabsorption from 93.1 +/- 3.94 to 88.3 +/- 2.29%. This study indicates that in the immediate postnatal period, glomerulotubular balance is disturbed.
Six lambs were delivered by caesarean section at 139 to 145 days of gestation. Birth was associated with a rise in glomerular filtration rate from 4.81 +/- 0.62 to 5.90 +/- 0.74 ml/min and a transient natriuresis secondary to a fall in fractional sodium reabsorption from 93.1 +/- 3.94 to 88.3 +/- 2.29%. This study indicates that in the immediate postnatal period, glomerulotubular balance is disturbed.