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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
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Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
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Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
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Skin and soft tissue infections, active component, U.S. Armed Forces, January 2016-September 2020.

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    Skin and soft tissue infections (SSTIs) affected over 210,000 U.S. military members between 2016-2020. Higher rates were seen in younger, junior enlisted personnel, highlighting a need for targeted prevention strategies.

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    Area of Science:

    • Military Health
    • Infectious Diseases
    • Epidemiology

    Background:

    • Skin and soft tissue infections (SSTIs) represent a significant health concern in military populations.
    • Understanding the incidence and risk factors for SSTIs is crucial for maintaining force readiness.

    Purpose of the Study:

    • To determine the incidence, trends, and associated factors of SSTIs among active component U.S. military members.
    • To assess the operational and healthcare burden of SSTIs in the military.

    Main Methods:

    • Retrospective analysis of incident SSTI cases from January 1, 2016, to September 30, 2020.
    • Inclusion of data from active component U.S. military members, including those in theaters of operations.
    • Categorization of SSTI diagnoses and analysis of incidence rates by demographic and service-related factors.

    Main Results:

    • Over 210,000 incident SSTI cases were recorded, with cellulitis/abscess being the most common diagnosis.
    • Incidence rates declined by 21.9% over the study period.
    • Higher SSTI rates were associated with younger age, recruit/trainee status, and junior enlisted rank.

    Conclusions:

    • SSTIs impose a substantial operational and healthcare burden on the U.S. military.
    • Targeted prevention, early diagnosis, and treatment strategies are needed, especially in high-risk settings like initial military training.