Related Experiment Video
Updated: Nov 6, 2025

Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance
Published on: December 13, 2024
The SoftWipe tool and benchmark for assessing coding standards adherence of scientific software.
Adrian Zapletal1,2, Dimitri Höhler1,2, Carsten Sinz2
1Computational Molecular Evolution group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany.
Scientific software quality is crucial for reliable research. A new tool, SoftWipe, ranks 48 computational tools on coding standards adherence, aiding software selection and paper reviews.
Area of Science:
- Scientific software is integral across all research domains for generating novel insights.
- Ensuring high-quality scientific software is essential for reproducible and accurate research outcomes.
Background:
- Coding standards adherence in scientific software is infrequently evaluated.
- Poor coding practices can compromise the integrity of scientific results.
- Lack of standardized assessment hinders reliable scientific software selection.
Purpose of the Study:
- To introduce SoftWipe, an open-source tool and benchmark for assessing scientific software.
- To provide a relative ranking of coding standards adherence for computational tools.
- To support the review process for software publications and inform software choices.
Main Methods:
- Developed an open-source tool named SoftWipe.
- Created a benchmark dataset comprising 48 computational tools.
- Established a methodology for relative ranking of software coding standards adherence.
Main Results:
- SoftWipe provides a relative ranking of coding standards adherence for 48 diverse scientific software tools.
- The benchmark facilitates a comparative assessment of software quality.
- Identified variations in coding standards adherence across different research areas.
Conclusions:
- SoftWipe offers a valuable resource for evaluating scientific software quality.
- The tool can enhance the review process for scientific software papers.
- SoftWipe aids researchers in making informed decisions when selecting scientific software.
More Related Videos
Related Concept Videos
Statistical Software for Data Analysis and Clinical Trials
Protein Folding Quality Check in the RER
Quantifying and Rejecting Outliers: The Grubbs Test
Guidelines and Strategies for Safe Computer Charting
Maintain Confidentiality and Security:
Multiple Comparison Tests
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
Comparing Copy Number Variations and SNPs
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...

