Relationship between the Severity of Coronary Artery Disease and Overactive Bladder

Overactive bladder is a urological disease that can seriously impair a person's quality of life, however its etiology remains unclear. The aim of this study was to evaluate the relationship between overactive bladder and SYNTAX score, which is based on coronary angiographic imaging to evaluate the severity of coronary artery disease.

A total of 380 patients diagnosed with coronary artery disease by coronary angiography were included in the study. Each participant completed the Overactive Bladder-Validated 8 questionnaire. The patients were divided into two groups as overactive bladder (n = 177; score ≥ 8), and non-overactive bladder (n = 203; score < 8). SYNTAX scores were calculated for both groups and compared.

The SYNTAX score was significantly higher in the patients with overactive bladder (25.4 ± 4.2) than in those without an overactive bladder (18.3 ± 3.4) (p < 0.001). In addition, age, smoking rate, body mass index and diabetes mellitus were significantly higher and heart rate was significantly lower in the overactive bladder group (p < 0.001). In logistic regression analysis, the SYNTAX score was the sole independent predictor of overactive bladder (odds ratio: 1.47, 95% confidence interval: 1.35-9.19, p < 0.001).

Our study suggests that the presence of a high SYNTAX score in patients with coronary artery disease may be associated with overactive bladder.