Type 2 Brugada Electrocardiogram Pattern Due to Supra-Therapeutic Phenytoin Level
Haris Iftikhar1, Khalid Bashir1
1Emergency Medicine, Hamad Medical Corporation, Doha, QAT.
Cureus
|May 12, 2021
Summary
Brugada phenocopy (BP) can mimic Brugada syndrome (BS) due to reversible causes like medications. This study details a case of type 2 BP from high phenytoin levels, resolving with dose adjustment.
Area of Science:
- Cardiology
- Clinical Electrophysiology
- Pharmacology
Background:
- Brugada syndrome (BS) is an inherited cardiac arrhythmia causing sudden cardiac death without structural heart abnormalities.
- Brugada phenocopy (BP) describes ECG patterns resembling BS, often due to reversible factors like medications or electrolyte imbalances.
- Sodium channel blocking antiepileptic drugs (AEDs), particularly phenytoin, are known to induce Brugada-like ECG patterns.
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