Antimicrobial Stewardship: A Review for Internal Medicine Physicians

Syeda Sahra1, Abdullah Jahangir2, Vincent De Chavez3

  • 1Internal Medicine, Staten Island University Hospital Northwell, Staten Island, USA.

Cureus
|May 12, 2021
PubMed

Insights

Antimicrobial stewardship is crucial to combat resistant pathogens and prevent healthcare system collapse. Implementing Antimicrobial Stewardship Programs (ASP) provides physicians with strategies for appropriate antibiotic use and management of infections.

Area of Science:

  • Infectious Diseases
  • Internal Medicine
  • Public Health

Background:

  • Rising antimicrobial resistance poses a significant threat to global health.
  • Indiscriminate antibiotic use has led to widespread pathogen resistance, limiting treatment options.
  • Gram-negative bacteria are increasingly resistant to major antibiotic classes.

Purpose of the Study:

  • To review the importance of Antimicrobial Stewardship Programs (ASP) for internal medicine physicians and residents.
  • To provide an educational guide on evidence-based ASP implementation.
  • To discuss clinical scenarios, antibiotic indications, and newer treatment options.

Main Methods:

  • Literature review on antimicrobial stewardship principles and practices.
  • Discussion of common clinical scenarios and antibiotic selection.
  • Highlighting the role of the healthcare team in ASPs.
  • Review of adverse effects and newer antibiotic agents.

Main Results:

  • Antimicrobial resistance necessitates structured stewardship programs.
  • Physicians require guidance on appropriate antibiotic indications and pathogen-guided therapy.
  • Newer antibiotics offer alternatives but require judicious use.
  • Multidisciplinary team involvement is key to successful ASPs.

Conclusions:

  • Antimicrobial Stewardship Programs are essential for preserving antibiotic efficacy.
  • Education and evidence-based strategies are vital for effective ASP implementation.
  • A collaborative healthcare approach is necessary to combat antimicrobial resistance.

Related Concept Videos

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
91
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
73
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
3.3K
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
691
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
70
Antibiotic Selection00:57

Antibiotic Selection

Overview
56.9K