Characteristics of cerebral sinus venous thrombosis in men

Naaem Simaan1, Andrei Filioglo1, Asaf Honig1

  • 1Departments of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Insights

Cerebral sinus venous thrombosis (CSVT) affects men differently than women. Younger men show higher rates of Behcet's disease, while older men have more malignancies as CSVT causes.

Area of Science:

  • Neurology
  • Vascular Medicine
  • Stroke Research

Background:

  • Cerebral sinus venous thrombosis (CSVT) is a rare stroke subtype.
  • CSVT is more prevalent in women, but male-specific data are limited.

Purpose of the Study:

  • To investigate male-specific characteristics and risk factors in cerebral sinus venous thrombosis.
  • To compare CSVT presentation and outcomes between male and female patients.

Main Methods:

  • Retrospective analysis of consecutive CSVT patients (2005-2020).
  • Comparison of demographics, clinical presentation, and outcomes between sexes.
  • Subgroup analysis of male patients based on age (<35 vs. >35 years).

Main Results:

  • Males constituted 31.3% of 150 CSVT patients.
  • Males exhibited higher rates of prior thrombotic events, malignancies, and Behcet's disease.
  • Malignancies were more common in older males; Behcet's disease in younger males.

Conclusions:

  • Significant sex-specific differences exist in CSVT risk factors.
  • Behcet's disease is a key factor in younger males with CSVT.
  • Malignancies are primary drivers of CSVT in older males.
Abstract

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