Related Experiment Video
Updated: Nov 6, 2025
07:15
An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
9.9K
Nutraceuticals and microbiota.
Luis E Díaz-Orozco1,2, Nahum Méndez-Sánchez3,2
1National Autonomous University of Mexico, Mexico City, Mexico.
Minerva Gastroenterology
|May 12, 2021
Summary
Nutraceuticals show potential for chronic disease management by targeting the gut microbiome. Further research and technological advancements are needed to establish their efficacy and expand the group of established nutraceuticals.
Area of Science:
- Nutritional Science
- Microbiology
- Gastroenterology
Background:
- Nutraceuticals, derived from food, offer physiological benefits and chronic disease protection.
- Their role in altering microbiome composition for disease prevention and therapy is increasingly recognized.
- Current research faces challenges due to undefined 'healthy' microbiome states and dysbiosis concepts.
Purpose of the Study:
- To assess the potential of nutraceuticals as microbiome-targeted therapies.
- To explore the gut-liver axis in digestive and chronic liver diseases.
- To identify microbiome-targeted nutraceuticals for clinical research and therapeutic applications.
Main Methods:
- Review of current literature on nutraceuticals and microbiome manipulation.
- Analysis of the gut-liver axis in pathogenesis and progression of digestive diseases.
- Evaluation of emerging technologies for microbiome assessment.
Main Results:
- Nutraceuticals show promise in modulating the gut microbiome for therapeutic benefits.
- The gut-liver axis is a key pathway influenced by microbiome alterations.
- Consistent results from microbiome-targeted nutraceuticals may lead to inclusion in clinical trials.
Conclusions:
- Nutraceuticals hold potential as microbiome-targeted therapies for chronic diseases.
- Further research, including advanced microbiome assessment, is crucial.
- Quality microbiome-targeted nutraceuticals can offer significant health benefits.
Related Concept Videos
01:29Microorganisms in Medicine and Therapeutics
599
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
599
02:11The Roles of Bacteria and Fungi in Plant Nutrition
45.3K
Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
45.3K
01:27Microorganisms in Agriculture and Food industry
759
Microorganisms play a crucial role in agriculture and the food industry, contributing to soil fertility, crop protection, and food production. Their functions range from nitrogen fixation and biopesticide production to fermentation and food preservation, making them indispensable to sustainable farming and food safety.Role in AgricultureNitrogen-fixing bacteria, such as Rhizobium (symbiotic) and Azotobacter (free-living), convert atmospheric nitrogen into ammonia through biological nitrogen...
759
01:29Bacterial Flora of the Large Intestine
823
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
823
01:28Microbial Nutrition
613
Organisms exhibit remarkable metabolic diversity, categorized based on how they acquire energy and carbon. These strategies enable survival in various ecological niches and are essential for maintaining energy flow and nutrient cycling within ecosystems.Energy and Carbon SourcesOrganisms are classified as phototrophs or chemotrophs based on energy acquisition. Phototrophs use light as their energy source, while chemotrophs rely on oxidizing chemical compounds. Further differentiation arises...
613
01:18Surface Membrane Barriers
1.9K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.9K