Pitfalls in Frozen Section: A Case of Incidental Papillary Mesothelioma

Elina Shkolnik1, Jenna Marcus1, Debra S Heller1

  • 112286Rutgers-New Jersey Medical School, Newark, NJ, USA.

Insights

Well-differentiated papillary mesothelioma is a rare, benign peritoneal lesion in women. Recognizing this condition is crucial to avoid misdiagnosis as serous carcinoma during gynecological surgeries.

Area of Science:

  • Gynecologic Pathology
  • Surgical Pathology

Background:

  • Mesothelial lesions can be challenging to diagnose.
  • Papillary mesothelioma is an uncommon benign neoplasm.

Observation:

  • An incidental case of well-differentiated papillary mesothelioma was found during a hysterectomy for endometrial carcinoma.
  • The lesion occurred in the peritoneum of a woman.

Findings:

  • Well-differentiated papillary mesothelioma is a benign mesothelial lesion.
  • It can be recurrent despite its benign nature.

Implications:

  • Familiarity with this entity is essential for accurate intraoperative diagnosis.
  • Prevents misinterpretation as malignant serous carcinoma, improving patient management.

Related Concept Videos