Related Experiment Video
Updated: Nov 6, 2025

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
Published on: August 13, 2017
Lengthening After Nonvascularized Fibula Grafting for Large Postinfective Bone Defect: A Case Report with Long
Deepika Pinto1, Rujuta Mehta, Mandar Agashe
1Department of Pediatric Orthopaedics, Bai Jerbai Wadia Hospital for Children, Mumbai, India.
Insights
Distraction osteogenesis can effectively lengthen the tibial regenerate in children after nonvascularized fibula grafting for postinfective tibial gap nonunion, promoting good functional recovery.
Area of Science:
- Pediatric Orthopedics
- Regenerative Medicine
- Limb Reconstruction Surgery
Background:
- Postinfective tibial gap nonunion presents a significant challenge in pediatric limb reconstruction.
- Nonvascularized fibula grafting is a common method for addressing large bone defects.
- Distal tibial physeal arrest can lead to limb length discrepancies.
Observation:
- A 10-month-old boy with a large tibial defect due to osteomyelitis underwent fibula autografting.
- The patient experienced distal tibial physeal arrest, resulting in progressive limb shortening.
- Two sessions of distraction osteogenesis were performed on the grafted segment.
Findings:
- The tibial regenerate demonstrated successful lengthening through distraction osteogenesis.
- A total lengthening of 9 cm was achieved over two distraction osteogenesis procedures.
- The patient showed good functional recovery by 11.5 years of age.
Implications:
- This case highlights the potential of distraction osteogenesis in lengthening the tibial regenerate in pediatric patients.
- Nonvascularized fibula grafts can serve as a viable substrate for subsequent limb lengthening.
- Successful limb lengthening can lead to improved function and quality of life in children with bone defects.
Case:
We describe a case of lengthening of the tibial regenerate after nonvascularized fibula grafting, for postinfective tibial gap nonunion in a child. A large tibial defect secondary to osteomyelitis in a 10-month-old boy was reconstructed using a 5-cm fibula autograft. Concomitant distal tibial physeal arrest led to progressive shortening. Distraction osteogenesis was performed, through the grafted segment, on 2 occasions-at the ages of 3.5 and 8 years-to achieve total lengthening of 9 cm and good functional recovery at 11.5 years of age.
Conclusion:
The tibial regenerate after nonvascularized fibula grafting in children has good potential for distraction osteogenesis.
More Related Videos
08:20A Reliable and Reproducible Critical-Sized Segmental Femoral Defect Model in Rats Stabilized with a Custom External Fixator
Published on: March 24, 2019
06:38Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
Published on: October 12, 2016