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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
832
Reproducibility and Interobserver Agreement of Different Thyroid Imaging and Reporting Data Systems (TIRADS)
Yulia P Sych1, Valentin V Fadeev1, Elena P Fisenko2
1Department of Endocrinology 1 at I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russian Federation.
European Thyroid Journal
|May 13, 2021
Summary
The Kwak
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Thyroid nodules require accurate malignancy risk assessment.
- Thyroid Imaging Reporting and Data Systems (TIRADS) aim to standardize this assessment.
- Reproducibility of TIRADS remains a concern.
Purpose of the Study:
- To assess interobserver variability and diagnostic performance of Kwak's modification (Kw-TIRADS) and European TIRADS (EU-TIRADS).
Main Methods:
- Two independent specialists evaluated 153 thyroid nodules from 149 patients.
- Ultrasound images were assessed in a blinded manner.
- Interobserver agreement and diagnostic performance were analyzed.
Main Results:
- Substantial interobserver agreement was found for both Kw-TIRADS (κ=0.52) and EU-TIRADS (κ=0.67).
- Strong correlations existed between the two systems (Spearman's ρ ≈ 0.7).
- Sensitivity for cancer diagnosis was high (90-95%), with specificity around 60% for both.
Conclusions:
- Despite variability in feature descriptions, both Kw-TIRADS and EU-TIRADS show potential as useful clinical tools.
- These TIRADS classifications aid in evaluating thyroid nodule malignancy risk.
- Further standardization may enhance diagnostic performance.
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