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High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
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Ionizable Drug Self-Associations and the Solubility Dependence on pH: Detection of Aggregates in Saturated Solutions

Elisabet Fuguet1,2, Xavier Subirats1, Clara Ràfols1

  • 1Departament d'Enginyeria Química i Química Analítica and Institut de Biomedicina (IBUB), Universitat de Barcelona, Martí i Franquès 1-11, Barcelona E-08028, Spain.

Molecular Pharmaceutics
|May 13, 2021
PubMed

Keywords:
Henderson−Hasselbalch relationshipsdrug−buffer complexesmass spectrometryshake-flask methodsolubility−pHsub-micellar aggregates

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