Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Signaling01:30

Bacterial Signaling

38.0K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
38.0K
Overview of Exosomes01:36

Overview of Exosomes

3.1K
Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...
3.1K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

599
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
599
Biofilms01:29

Biofilms

589
Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
589
Intracellular Movement of Viruses and Bacteria01:10

Intracellular Movement of Viruses and Bacteria

3.1K
Intracellular bacteria and viruses often comprise a group of highly infectious pathogens that can cause several diseases. Bacterial pathogens include those belonging to the genus Rickettsia responsible for conditions such as rocky mountain spotted fever and the Mediterranean spotted fever; Chlamydia, a genus responsible for a sexually transmitted disease; Coxiella burnetii, an agent responsible for Q fever. Viral pathogens include vaccinia—a poxvirus, and herpes simplex virus—a...
3.1K
Bacterial Translocation and Protein Secretion01:26

Bacterial Translocation and Protein Secretion

201
Bacterial protein secretion involves translocation systems to ensure proteins reach their designated locations, including the plasma membrane, periplasm, outer membrane, or the external environment. These translocation systems are vital for bacterial physiology, supporting processes like membrane assembly, enzymatic activity in the periplasm, and interactions with the external environment. The division of labor between Sec and Tat pathways ensures efficiency in handling proteins with diverse...
201

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of influenza and pneumococcal vaccines on inflammatory response during suppressive antiretroviral therapy.

AIDS (London, England)·2026
Same author

Transcriptomic profiling of the ovarian immune landscape reveals distinct macrophage subsets and activation of the NLRP3 inflammasome likely contributing to accelerated follicular atresia in classic galactosemia.

Cell communication and signaling : CCS·2026
Same author

Functional Blood-Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery.

Advanced healthcare materials·2026
Same author

Conjugating M13 bacteriophage targeting folate receptor alpha with multiple photosensitizers: a flexible phototheranostic platform against ovarian cancer.

Journal of materials chemistry. B·2026
Same author

Bacterial dysbiosis, cervicovaginal human papillomaviruses and inflammation persist in women living with HIV-1 after a year of antiretroviral treatment.

The Journal of infectious diseases·2026
Same author

Longitudinal T-Cell Phenotypic Dynamics During Sustained Antiretroviral Therapy in People With HIV.

Open forum infectious diseases·2026

Related Experiment Video

Updated: Nov 5, 2025

Author Spotlight: Accelerating Research on Bacterial Extracellular Vesicles Separation and Heterogeneity
06:39

Author Spotlight: Accelerating Research on Bacterial Extracellular Vesicles Separation and Heterogeneity

Published on: September 1, 2023

3.4K

Microbiota-host communications: Bacterial extracellular vesicles as a common language.

Rogers A Ñahui Palomino1, Christophe Vanpouille1, Paolo E Costantini1,2

  • 1Section on Intercellular Interaction, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America.

Plos Pathogens
|May 13, 2021
PubMed
Summary

Extracellular vesicles (EVs) from bacteria mediate host communication by transporting molecules. Understanding bacterial EVs offers potential for new therapeutics and diagnostics.

More Related Videos

Characterization of Immune Cell-derived Extracellular Vesicles and Studying Functional Impact on Cell Environment
10:09

Characterization of Immune Cell-derived Extracellular Vesicles and Studying Functional Impact on Cell Environment

Published on: June 2, 2020

7.1K
Scalable Isolation and Purification of Extracellular Vesicles from Escherichia coli and Other Bacteria
09:56

Scalable Isolation and Purification of Extracellular Vesicles from Escherichia coli and Other Bacteria

Published on: October 13, 2021

4.2K

Related Experiment Videos

Last Updated: Nov 5, 2025

Author Spotlight: Accelerating Research on Bacterial Extracellular Vesicles Separation and Heterogeneity
06:39

Author Spotlight: Accelerating Research on Bacterial Extracellular Vesicles Separation and Heterogeneity

Published on: September 1, 2023

3.4K
Characterization of Immune Cell-derived Extracellular Vesicles and Studying Functional Impact on Cell Environment
10:09

Characterization of Immune Cell-derived Extracellular Vesicles and Studying Functional Impact on Cell Environment

Published on: June 2, 2020

7.1K
Scalable Isolation and Purification of Extracellular Vesicles from Escherichia coli and Other Bacteria
09:56

Scalable Isolation and Purification of Extracellular Vesicles from Escherichia coli and Other Bacteria

Published on: October 13, 2021

4.2K

Area of Science:

  • Microbiology
  • Cell Biology
  • Biochemistry

Background:

  • Bacteria, both gram-negative and gram-positive, release extracellular vesicles (EVs).
  • Bacterial EVs are comparable in size to mammalian EVs and carry diverse bioactive molecules.
  • These EVs are crucial in bacteria-host and bacteria-bacteria interactions, influencing health and disease.

Purpose of the Study:

  • To review the current knowledge on bacterial EVs.
  • To focus on the discovery, isolation, biogenesis, and role of bacterial EVs in microbiota-host communication.
  • To explore the translational potential of bacterial EVs in therapeutics and diagnostics.

Main Methods:

  • Literature review of current research on bacterial EVs.
  • Analysis of studies focusing on bacterial EV biogenesis and function.
  • Synthesis of information regarding the role of bacterial EVs in host interactions.

Main Results:

  • Bacterial EVs are increasingly studied for their role in intercellular communication.
  • EVs transport proteins, nucleic acids, lipids, and metabolites, mediating diverse biological effects.
  • Growing evidence links bacterial EVs to both beneficial and pathogenic processes in host interactions.

Conclusions:

  • Bacterial EVs are significant mediators of microbiota-host communication.
  • Further research into bacterial EV mechanisms can lead to novel diagnostic and therapeutic strategies.
  • The field of bacterial EV science is rapidly advancing with significant translational potential.