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Biocompatible diameter-oscillating fiber with microlens endface.

Jingyang Lian, Bin He, Wenlong Wang

    Optics Express
    |May 14, 2021
    PubMed
    Summary
    This summary is machine-generated.

    Researchers developed a novel diameter-oscillating fiber (DOF) with a microlens for advanced biophotonics. This biocompatible fiber manages ultrashort laser pulse dispersion, enhancing multiphoton microscopy applications in biological tissues.

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    Area of Science:

    • Biophotonics
    • Optical Fiber Technology
    • Materials Science

    Background:

    • Optical fibers are crucial in life sciences for applications like laser delivery and biosensing.
    • Advanced multiphoton biophotonics requires precise control over ultrashort laser pulses, posing significant challenges.

    Purpose of the Study:

    • To develop a novel optical fiber for improved ultrashort laser pulse management in biophotonics.
    • To address the dispersion challenges in near-infrared multiphoton biophotonics.

    Main Methods:

    • Fabrication of a flexible diameter-oscillating fiber (DOF) using Polydimethylsiloxane (PDMS) elastomers.
    • Incorporation of a microlens at the fiber endface.
    • Adjustable diameter variation and period for tailored dispersion management.

    Main Results:

    • The DOF provides accurate dispersion management by longitudinally varying its diameter.
    • Minimized net dispersion and reduced temporal broadening of ultrashort laser pulses.
    • The endface microlens facilitates laser scanning, focusing, and fluorescence excitation.

    Conclusions:

    • The developed biocompatible DOF offers effective dispersion control for ultrashort laser pulses.
    • The DOF with a microlens is promising for advanced biophotonic applications, especially deep-tissue multiphoton microscopy.