Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

NMR Spectrometers: Resolution and Error Correction01:14

NMR Spectrometers: Resolution and Error Correction

886
When magnetic nuclei in a sample achieve resonance and undergo relaxation, the signal detected in NMR is an approximately exponential free induction decay. Fourier transform of an exponential decay yields a Lorentzian peak in the frequency domain. Lorentzian peaks in an NMR spectrum are defined by their amplitude, full width at half maximum, and position, where the peak width is governed by the spin-spin relaxation time alone. In real experiments, however, the applied magnetic field is rendered...
886

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A clinical evaluation of amlexanox oral adhesive pellicles in the treatment of recurrent aphthous stomatitis and comparison with amlexanox oral tablets: a randomized, placebo controlled, blinded, multicenter clinical trial.

Trials·2009
Same author

Long-term assessment of bladder and bowel dysfunction after radical hysterectomy.

Gynecologic oncology·2009
Same author

Oxidative stress contributes to silica nanoparticle-induced cytotoxicity in human embryonic kidney cells.

Toxicology in vitro : an international journal published in association with BIBRA·2009
Same author

A rapid and simple method for identifying Mycobacterium tuberculosis W-Beijing strains based on detection of a unique mutation in Rv0927c by PCR-SSCP.

Microbes and infection·2009
Same author

CO oxidation over AuPd(100) from ultrahigh vacuum to near-atmospheric pressures: the critical role of contiguous Pd atoms.

Journal of the American Chemical Society·2009
Same author

Daunorubicin-loaded magnetic nanoparticles of Fe(3)O(4) greatly enhance the responses of multidrug-resistant K562 leukemic cells in a nude mouse xenograft model to chemotherapy.

Zhongguo shi yan xue ye xue za zhi·2009

Related Experiment Video

Updated: Nov 5, 2025

Three-dimensional Super Resolution Microscopy of F-actin Filaments by Interferometric PhotoActivated Localization Microscopy iPALM
11:57

Three-dimensional Super Resolution Microscopy of F-actin Filaments by Interferometric PhotoActivated Localization Microscopy iPALM

Published on: December 1, 2016

11.0K

Profile-based intensity and frequency corrections for single-snapshot spatial frequency domain imaging.

Mai Dan, Meihui Liu, Wenxing Bai

    Optics Express
    |May 14, 2021
    PubMed
    Summary

    Profile-based corrections improve spatial frequency domain (SFD) imaging by reducing surface profile errors. This method enhances accuracy in extracting optical properties from tissue, showing clinical feasibility.

    More Related Videos

    Sample Drift Correction Following 4D Confocal Time-lapse Imaging
    10:04

    Sample Drift Correction Following 4D Confocal Time-lapse Imaging

    Published on: April 12, 2014

    16.7K
    Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
    13:44

    Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns

    Published on: August 30, 2013

    43.2K

    Related Experiment Videos

    Last Updated: Nov 5, 2025

    Three-dimensional Super Resolution Microscopy of F-actin Filaments by Interferometric PhotoActivated Localization Microscopy iPALM
    11:57

    Three-dimensional Super Resolution Microscopy of F-actin Filaments by Interferometric PhotoActivated Localization Microscopy iPALM

    Published on: December 1, 2016

    11.0K
    Sample Drift Correction Following 4D Confocal Time-lapse Imaging
    10:04

    Sample Drift Correction Following 4D Confocal Time-lapse Imaging

    Published on: April 12, 2014

    16.7K
    Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
    13:44

    Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns

    Published on: August 30, 2013

    43.2K

    Area of Science:

    • Biomedical Optics
    • Medical Imaging
    • Photon Counting Detection

    Background:

    • Spatial Frequency Domain (SFD) imaging is crucial for non-invasively measuring tissue optical properties.
    • Surface topography can introduce significant errors in SFD measurements, affecting accuracy.
    • Existing methods struggle to fully compensate for these profile-induced distortions.

    Purpose of the Study:

    • To introduce profile-based intensity and frequency corrections for single-snapshot SFD imaging.
    • To mitigate the impact of sample surface profiles on optical property extraction.
    • To enhance the accuracy and reliability of SFD imaging in complex samples.

    Main Methods:

    • Developed an adaptive scheme to adjust the projected sinusoidal pattern's frequency based on surface topography.
    • Implemented Minnaert's correction to compensate for intensity variations due to surface profiles.
    • Utilized a single-pixel photon-counting detection system for high-sensitivity SFD imaging.

    Main Results:

    • Reduced errors in extracting absorption coefficients by an average of 40%.
    • Reduced errors in extracting reduced scattering coefficients by an average of 10%.
    • Demonstrated clinical feasibility through an in vivo topography experiment on opisthenar vessels.

    Conclusions:

    • Profile-based corrections significantly improve the accuracy of optical property extraction in SFD imaging.
    • The proposed method effectively compensates for surface profile effects, enhancing measurement reliability.
    • This technique shows promise for accurate in vivo optical property measurements in clinical applications.