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An Unbiased Approach of Sampling TEM Sections in Neuroscience
Published on: April 13, 2019
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Sampling theory and sampling uncertainty.
Summary
Chemical measurements aid rational decisions about materials, but both analysis and sampling introduce uncertainty. This uncertainty must be considered for accurate decision-making in various fields.
Area of Science:
- Analytical Chemistry
- Measurement Science
Background:
- Chemical measurements are crucial for informed decision-making in diverse sectors like manufacturing, commerce, and healthcare.
- Decisions rely on understanding the properties of specific 'targets' or masses of material.
Purpose of the Study:
- To highlight the inherent uncertainty in chemical measurements and sampling processes.
- To emphasize the importance of accounting for all sources of uncertainty in decision-making.
Main Methods:
- Discusses the principles of chemical measurement and sampling.
- Explains how uncertainty arises from both the analytical process and sample selection.
Main Results:
- Chemical analysis inherently involves uncertainty.
- Sampling a target material introduces additional, significant uncertainty.
- Both analytical and sampling uncertainties impact the reliability of decisions.
Conclusions:
- All sources of uncertainty, including sampling, must be quantified and considered.
- Accurate decision-making requires a comprehensive understanding of measurement and sampling uncertainty.
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