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Published on: September 12, 2019
Development of endometrial cancer after long-term usage of the levonorgestrel-releasing intrauterine system
Alexander Steshenko1, Leila Hanna2, Damian Collins3
1Obstetrics and Gynaecology, Queen Elizabeth Hospital, London, London, UK asteshenko@nhs.net.
Abstract:
A 52-year-old long-term user of the levonorgestrel-releasing intrauterine system (LNG-IUS) presented with vaginal bleeding. Endometrial biopsy was performed and revealed endometrioid adenocarcinoma. The patient had a laparoscopic hysterectomy and bilateral salpingo-oophorectomy. Endometrial cancer is rare in women with LNG-IUS as only seven cases have been published in the literature. Although scientific evidence shows LNG-IUS has a protective effect on the endometrium from developing cancer, our report highlights the importance of clinicians to be vigilant in cases of women with LNG-IUS who develop intermittent vaginal bleeding.
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