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Updated: Nov 5, 2025

Thin Film Composite Silicon Elastomers for Cell Culture and Skin Applications: Manufacturing and Characterization
Published on: July 3, 2018
K Kasim Mohamed1, R Fathima Banu1, V Anand Kumar1
1Department of Prosthodontics, Faculty of Dental Science, Sri Ramachandra Institute of Higher Education and Research, Chennai 600116, India.
This study examined the chemical stability and surface characteristics of polyvinyl siloxane (PVS), a material commonly used in dentistry for impressions. Researchers prepared PVS discs and placed them in different environments, including methanol, human saliva, and artificial nasal fluid. Using gas chromatography-mass spectrometry (GC-MS), they analyzed the samples at various time points to detect any chemical changes. The results showed that PVS did not release harmful compounds over a two-week period. The surface of the material remained unchanged, suggesting it could be used in other applications beyond dental impressions. The findings indicate that PVS is chemically stable in simulated biological environments.
Area of Science:
Background:
Prior research has established that polyvinyl siloxane (PVS) is commonly used in dentistry for impressions. However, the long-term stability and component release from PVS in different media remain unclear. Existing studies have focused on mechanical properties rather than chemical composition and surface changes. This gap motivated the need to investigate PVS beyond its traditional use. No prior work had resolved the chemical behavior of PVS in simulated biological environments. Understanding these properties could help expand PVS applications. Researchers have not yet determined if PVS remains chemically inert over time. This uncertainty drove the current study to explore PVS in non-dental contexts. The findings may provide insights into broader material applications.
Purpose Of The Study:
The aim of the study was to evaluate the surface characteristics and chemical release of PVS in various environments. The researchers wanted to determine if PVS could be used beyond dental impressions. They focused on assessing the material’s stability in simulated biological fluids. The study aimed to identify any potential chemical changes over time. They also sought to explore the suitability of PVS for other applications. The motivation stemmed from the lack of data on PVS in non-dental settings. The team wanted to assess whether PVS remains chemically inert. The study’s goal was to provide evidence for the material’s broader use.
Main Methods:
The researchers prepared 40 PVS discs with specific dimensions and perforations. They divided the samples into four groups for different analyses. Group 1 was placed in methanol and analyzed at multiple time points. Group 2 was immersed in human saliva for GC-MS analysis. Group 3 was placed in artificial nasal fluid for similar testing. Group 4 underwent surface analysis after exposure to saliva and nasal fluid. The study used gas chromatography-mass spectrometry (GC-MS) to detect compounds. The surface characteristics were evaluated using standard analytical techniques. The experimental setup allowed for tracking changes in PVS over time.
Main Results:
Group 1 showed the release of several compounds, including Dodecanoic acid and Cyclononasiloxane on Day 1. At 24 hours, Group 2 revealed additional compounds like 2-Decene and Lauryl acetate. Group 3 had 32 compounds detected, but with shorter retention times. No significant surface changes were observed in Group 4 on Day 14. The study found no adverse component release from PVS over two weeks. The GC-MS analysis indicated chemical stability in all groups. The results suggest that PVS remains chemically inert in tested environments. The findings support the potential use of PVS beyond dental impressions.
Conclusions:
The authors propose that PVS remains chemically stable in various environments for two weeks. They suggest that the material does not release harmful components based on GC-MS results. The study implies that PVS could be suitable for non-dental applications. The findings indicate that surface characteristics remain unchanged over time. The authors suggest that PVS may have broader uses beyond impressions. The study supports the idea that PVS is inert in simulated biological fluids. The results do not confirm any essential role for PVS in other contexts. The authors propose further exploration of PVS in new applications.
Compounds like Dodecanoic acid, Cyclononasiloxane, and Lauryl acetate were detected in PVS samples.
The study used gas chromatography-mass spectrometry (GC-MS) to detect and analyze released compounds.
To assess the material’s stability and chemical release in simulated biological environments.
Methanol served as a control to compare PVS behavior in different solvents.
No adverse component release was observed in PVS over a 14-day period.
The findings suggest PVS could be suitable for applications beyond dental impressions.