Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Atomic Force Microscopy

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...

Overview of Microscopy Techniques

Overview of Microscopy Techniques

The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Optimal dimensionality and fundamental limits of proton stopping power estimation with photon-counting CT material decomposition.

Physics in medicine and biology·2026

Same author

Trends in age-sex-specific prevalence and incidence of antidepressant dispensation in the Nordic countries: a systematic review.

British journal of clinical pharmacology·2026

Same author

Growth of Low-Defect WSe<sub>2</sub> Film via High-Purity van der Waals Crystal Precursor.

ACS nano·2026

Same author

A molecule with half-Möbius topology.

Science (New York, N.Y.)·2026

Same author

Improving the Stability and Transferability of Effective ADMET Models by Adding Quantum Mechanical Descriptors.

Journal of chemical information and modeling·2026

Same author

Deep-learning-based spectral motion artifact correction on photon-counting cardiac CT images.

Physics in medicine and biology·2026

Search research articles

Related Experiment Video

Updated: Nov 5, 2025

Atomic Force Microscopy of Red-Light Photoreceptors Using PeakForce Quantitative Nanomechanical Property Mapping

Atomic Force Microscopy of Red-Light Photoreceptors Using PeakForce Quantitative Nanomechanical Property Mapping

Published on: October 24, 2014

Probing Molecular Excited States by Atomic Force Microscopy.

Shadi Fatayer¹, Florian Albrecht¹, Ivano Tavernelli¹

¹IBM Research-Zurich, Säumerstrasse 4, 8803 Rüschlikon, Switzerland.

Physical Review Letters

|May 14, 2021

Summary

Investigating molecular redox reactions using single charge injections revealed three neutralization pathways. This study quantifies excited state energies, offering insights into electron transfer and molecular optoelectronics.

More Related Videos

High-Speed Atomic Force Microscopy Imaging of DNA Three-Point-Star Motif Self Assembly Using Photothermal Off-Resonance Tapping

High-Speed Atomic Force Microscopy Imaging of DNA Three-Point-Star Motif Self Assembly Using Photothermal Off-Resonance Tapping

Published on: March 22, 2024

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair

Published on: May 24, 2017

Related Experiment Videos

Last Updated: Nov 5, 2025

Atomic Force Microscopy of Red-Light Photoreceptors Using PeakForce Quantitative Nanomechanical Property Mapping

Atomic Force Microscopy of Red-Light Photoreceptors Using PeakForce Quantitative Nanomechanical Property Mapping

Published on: October 24, 2014

High-Speed Atomic Force Microscopy Imaging of DNA Three-Point-Star Motif Self Assembly Using Photothermal Off-Resonance Tapping

High-Speed Atomic Force Microscopy Imaging of DNA Three-Point-Star Motif Self Assembly Using Photothermal Off-Resonance Tapping

Published on: March 22, 2024

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair

Published on: May 24, 2017

Area of Science:

Surface science
Molecular electronics
Quantum chemistry

Background:

Understanding molecular redox reactions is crucial for electron transfer and molecular optoelectronics.
Investigating charge injection on insulating films presents unique challenges.

Purpose of the Study:

To investigate the redox reactions of a single molecule on a multilayer insulating film.
To quantify the energy differences between ground and excited states using single-charge injections.
To compare experimental results with theoretical calculations.

Main Methods:

Utilizing an atomic force microscope for single charge injections.
Employing single-electron tunneling spectroscopy to measure energy transitions.
Performing density functional theory calculations for excited state energies.

Main Results:

Observed three distinct channels for molecular neutralization after positive charging.
Identified these channels as transitions to neutral ground, triplet excited, and singlet excited states.
Experimentally determined triplet and singlet excited state energies, showing good agreement with DFT calculations.

Conclusions:

Molecules in excited states can be controllably prepared on insulating surfaces.
Single-charge injection is a viable method for quantifying optical gap energies.
Provides fundamental insights into electron-attachment processes relevant to molecular optoelectronics.