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Updated: Nov 5, 2025

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Native aorto-ostial coronary lesions on CT coronary angiogram
Jan Y J Riley1,2, Kai'En Leong1, Kristian H Mortensen3
1Department of Radiology, Hammersmith Hospital, Imperial College Healthcare NHS trust, London, United Kingdom.
Insights
Aorto-ostial coronary lesions (AOLs) can be missed by invasive angiography. Computed tomography coronary angiogram (CTCA) effectively detects AOLs and surrounding anatomy, aiding in diagnosis.
Area of Science:
- Cardiovascular imaging
- Interventional cardiology
- Radiology
Background:
- Aorto-ostial coronary lesions (AOLs) pose significant risks and may be overlooked during invasive coronary angiography.
- The complex nature of AOLs necessitates advanced imaging techniques for accurate detection.
Purpose of the Study:
- To highlight the utility of computed tomography coronary angiogram (CTCA) in detecting AOLs.
- To present CTCA's advantage in visualizing surrounding anatomy and identifying diverse AOL etiologies.
- To introduce the "CIAO (TEDS)" mnemonic for comprehensive AOL assessment.
Main Methods:
- Review of CTCA imaging in patients with suspected or confirmed AOLs.
- Analysis of CTCA's sensitivity and specificity for AOL detection compared to invasive methods.
- Categorization of AOL etiologies using the "CIAO (TEDS)" framework.
Main Results:
- CTCA demonstrates high sensitivity and specificity for detecting AOLs.
- CTCA effectively visualizes perivascular anatomy, crucial for identifying non-atherosclerotic causes of AOLs.
- The "CIAO (TEDS)" mnemonic (Congenital anomalies, Compression, Iatrogenic, Arteritis, Other – Thrombus, Embolism, Dissection, Spasm) provides a structured approach to AOL assessment.
Conclusions:
- CTCA is a valuable tool for diagnosing AOLs, offering superior visualization of surrounding structures.
- CTCA facilitates the identification of a broad spectrum of AOL causes beyond atherosclerosis.
- The "CIAO (TEDS)" mnemonic serves as a practical aid for radiologists and cardiologists evaluating AOLs.
Abstract:
Aorto-ostial coronary lesions (AOLs) are important to detect due to the high risk of catastrophic consequences. Unfortunately, due to the complexities of these lesions, they may be missed on invasive coronary angiography. Computed tomography coronary angiogram (CTCA) is highly sensitive and specific in detecting AOLs, and has the additional advantage of demonstrating the surrounding anatomy. CTCA is particularly useful when assessing for AOL aetiologies in addition to atherosclerotic disease, e.g. Congenital anomalies, extrinsic Compression, Iatrogenic, Arteritis and Other, such as Thrombus, Embolism, Dissection and Spasm. This gives rise to "CIAO (TEDS)" as a proposed aide-mémoire and will form the structure of this pictorial review.
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