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Related Concept Videos

Types of RNA01:23

Types of RNA

70.1K
Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
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Types of RNA01:20

Types of RNA

7.8K
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA Performs Diverse...
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lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

9.2K
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
9.2K
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

3.1K
3.1K
Translational Regulation01:29

Translational Regulation

304
Translational regulation in prokaryotes ensures efficient protein synthesis by controlling ribosome access to mRNA. This regulation is mediated by secondary RNA structures, including translational riboswitches, RNA thermometers, and small RNAs (sRNAs), which respond to intracellular and environmental signals to modulate gene expression.Translational RiboswitchesRiboswitches in the leader region of mRNAs can regulate translation by altering the accessibility of the Shine-Dalgarno (SD) sequence,...
304
Bacterial RNA Polymerase00:43

Bacterial RNA Polymerase

31.4K
Unlike eukaryotes, bacteria use a single RNA Polymerase (RNAP) to transcribe all genes. The different subunits of bacterial RNAPhave distinct functions. The multisubunit structure of the bacterial RNAP helps the enzyme to maintain catalytic function, facilitate assembly, interact with DNA and RNA, and self-regulate its activity.
In most genes, the transcription site is a single base present upstream of the coding sequence. Though RNAP is a catalytically efficient enzyme, it does not recognize...
31.4K

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Related Experiment Video

Updated: Nov 5, 2025

A Non-Coding Small RNA MicC Contributes to Virulence in Outer Membrane Proteins in Salmonella Enteritidis
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A Non-Coding Small RNA MicC Contributes to Virulence in Outer Membrane Proteins in Salmonella Enteritidis

Published on: January 27, 2021

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Long noncoding RNAs in bacterial infection.

Nils Schmerer1, Leon N Schulte1,2

  • 1Institute for Lung Research, Philipps-University, Marburg, Germany.

Wiley Interdisciplinary Reviews. RNA
|May 14, 2021
PubMed
Summary

Long noncoding RNAs (lncRNAs) are emerging regulators in the immune system

Area of Science:

  • * Molecular Biology
  • * Immunology
  • * Genetics

Background:

  • * Infectious and inflammatory diseases are leading causes of global mortality.
  • * The mammalian immune system uses regulators to control inflammation and prevent damage.
  • * Long noncoding RNAs (lncRNAs) are a vast, understudied class of genomic transcripts.

Purpose of the Study:

  • * To review the roles of lncRNAs in host-pathogen interactions.
  • * To explore lncRNA involvement in immune responses to bacterial infections.
  • * To highlight lncRNAs in regulating inflammation and immune evasion.

Main Methods:

  • * Literature review of studies on lncRNAs and bacterial infections.
  • * Analysis of current understanding of lncRNA functions in immunity.
Keywords:
bacteriaimmunityinfectioninflammationlncRNA

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In Silico Identification and Characterization of circRNAs During Host-Pathogen Interactions

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Last Updated: Nov 5, 2025

A Non-Coding Small RNA MicC Contributes to Virulence in Outer Membrane Proteins in Salmonella Enteritidis
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In Silico Identification and Characterization of circRNAs During Host-Pathogen Interactions

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  • * Synthesis of data on host-pathogen interactions involving lncRNAs.

    • Main Results:

    • * lncRNAs are implicated in regulating innate and adaptive immunity.
    • * Bacterial pathogens may subvert host lncRNA networks.
    • * lncRNAs influence host cell responses to bacterial invasion.

    Conclusions:

    • * lncRNAs are critical players in host-pathogen interactions.
    • * Understanding lncRNA networks can reveal host mechanisms and microbial strategies.
    • * Further research into lncRNAs offers therapeutic potential for infectious diseases.