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Updated: Aug 16, 2026

Patch Clamp Recording of Ion Channels Expressed in Xenopus Oocytes
08:00

Patch Clamp Recording of Ion Channels Expressed in Xenopus Oocytes

Published on: October 15, 2008

Influence of the patch pipette glass on single acetylcholine channels recorded from Xenopus myocytes

L Rojas1, C Zuazaga

  • 1Institute of Neurobiology, University of Puerto Rico Medical Sciences Campus, San Juan 00901.

Neuroscience Letters
|May 16, 1988
PubMed

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Related Concept Videos

Patch Clamp01:18

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...