Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Post-traumatic Stress Disorder

Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...

Stress and Mental Health

Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...

Introduction to Stress and Lifestyle

Introduction to Stress and Lifestyle

Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...

Psychological and Sociocultural Causes of Schizophrenia

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...

Generalized Anxiety Disorder

Generalized Anxiety Disorder

Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...

Psychological Responses to Stress

Psychological Responses to Stress

Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Elevated IL-6 receptor expression on CD4+ T cells contributes to the increased Th17 responses in patients with chronic hepatitis B.

Virology journal·2011

Same author

Neurochemical plasticity of nitric oxide synthase isoforms in neurogenic detrusor overactivity after spinal cord injury.

Neurochemical research·2011

Same author

[Clinical significance of 5-HT and DA levels in serum and cerebrospinal fluid of the patients with delayed encephalopathy after acute carbon monoxide poisoning].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases·2011

Same author

Reconstitution of lysosomal NAADP-TRP-ML1 signaling pathway and its function in TRP-ML1(-/-) cells.

American journal of physiology. Cell physiology·2011

Same author

[The association between HBV genotyping and clinical characteristics and expression of TH1/TH2 cytokines].

Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology·2011

Same author

Bis[5-(2-pyrid-yl)pyrazine-2-carbonitrile]-silver(I) tetra-fluorido-borate.

Acta crystallographica. Section E, Structure reports online·2011

Same journal

Efficacy of PVCA classification in guiding management strategies for cervical vascular trauma.

Chinese journal of traumatology = Zhonghua chuang shang za zhi·2026

Same journal

Evaluation of teriparatide as a promoter of mandibular fracture healing: An observational clinical study.

Chinese journal of traumatology = Zhonghua chuang shang za zhi·2026

Same journal

Lego-like reconstruction of a complex floating knee using osteotomy-assisted exposure: A case report.

Chinese journal of traumatology = Zhonghua chuang shang za zhi·2026

Same journal

Functional outcomes in severe traumatic brain injury: A comparative study of intracranial pressure guided therapy vs. conventional management.

Chinese journal of traumatology = Zhonghua chuang shang za zhi·2026

Same journal

Intraocular foreign bodies in the posterior segment: Clinical characteristics, management, and visual outcomes.

Chinese journal of traumatology = Zhonghua chuang shang za zhi·2026

Same journal

A severity-aware multi-agent soft actor-critic framework for medical resource coordination in plateau disaster rescue.

Chinese journal of traumatology = Zhonghua chuang shang za zhi·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Nov 5, 2025

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment

Published on: December 6, 2024

PTSD: Past, present and future implications for China.

Yao-Guang Zhou¹, Zhi-Lei Shang², Fan Zhang³

¹Lab for Post-traumatic Stress Disorder, Faculty of Psychology and Mental Health, Naval Medical University, Shanghai, 200433, China.

Chinese Journal of Traumatology = Zhonghua Chuang Shang Za Zhi

|May 17, 2021

Summary

This summary is machine-generated.

Posttraumatic stress disorder (PTSD) research has advanced understanding of its symptoms, neurobiology, and treatments. Further research is crucial, especially in China, to develop targeted therapies and improve patient outcomes.

Keywords:

Epidemiology Mechanism Posttraumatic stress disorder Review Treatment

More Related Videos

Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

Published on: October 10, 2012

A Multiple Integrated Social Stress Model for Psychiatric Disorders in Female C57BL/6J Mice

A Multiple Integrated Social Stress Model for Psychiatric Disorders in Female C57BL/6J Mice

Published on: July 15, 2025

Related Experiment Videos

Last Updated: Nov 5, 2025

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment

Published on: December 6, 2024

Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

Published on: October 10, 2012

A Multiple Integrated Social Stress Model for Psychiatric Disorders in Female C57BL/6J Mice

A Multiple Integrated Social Stress Model for Psychiatric Disorders in Female C57BL/6J Mice

Published on: July 15, 2025

Area of Science:

Psychiatry
Neuroscience
Psychology

Background:

Posttraumatic stress disorder (PTSD) is a psychiatric condition characterized by symptoms following traumatic events.
Research has explored PTSD's epidemiology, biological mechanisms, and treatment, with prevalence ranging from 6.4% to 7.8% in the general population.

Purpose of the Study:

To review current understanding of PTSD, including its neurobiological underpinnings and therapeutic approaches.
To highlight the need for strengthened PTSD research in China and suggest avenues for advancement.

Main Methods:

Review of existing literature on PTSD epidemiology, genetics, neuroimaging, and treatment modalities.
Functional MRI studies examining brain regions like the medial prefrontal cortex, anterior cingulate cortex, amygdala, and hippocampus.

Main Results:

PTSD is associated with alterations in specific brain structures and their functional connectivity.
Cognitive behavior therapy-based psychotherapy, with or without medication, demonstrates treatment efficacy.
Challenges remain due to high comorbidity and complex pathogenesis, hindering the identification of specific biological targets.

Conclusions:

Despite progress, the complexity of PTSD pathogenesis necessitates further fundamental research for novel biomarkers and pharmacotherapies.
Strengthening PTSD research in China through national projects and collaborative efforts is critical for advancing understanding and treatment.