Innovative Medical Technology and the Treatment Decision-Making Process in Multiple Sclerosis: A Focus Group Study to...

Area of Science:

• Neurology
• Medical Technology
• Patient-Reported Outcomes

Background:

• Disease-modifying therapies (DMTs) for multiple sclerosis (MS) aim to reduce disease progression and relapse frequency.
• Current MS treatment administration includes oral, injectable, and infusion methods, complicating patient decision-making.
• A novel implantable device for MS treatment is under development, but patient perspectives remain unexplored.

Purpose of the Study:

• To understand the patient perspective on the treatment decision-making process in multiple sclerosis (MS).
• To explore patient attitudes and potential acceptance of an implantable device for MS treatment.

Main Methods:

• Focus groups were conducted with individuals diagnosed with multiple sclerosis (MS) in the Netherlands.
• Discussions covered treatment decision-making, the current treatment landscape, and attitudes toward an implantable device.
• An online survey quantified interest in the implantable device among MS patients.

Main Results:

• A key theme was the persistent uncertainty MS patients experience regarding treatment decisions (initiation, cessation, modification).
• Focus group participants (n=16) and survey respondents (n=93) showed general positivity towards the implantable device concept.
• Patients emphasized the necessity of guaranteed efficacy and safety for the implantable MS treatment.

Conclusions:

• Individuals with MS desire enhanced control over their disease and treatment journey.
• Implantable devices represent a potential advancement in the MS treatment landscape, possibly gaining patient acceptance.
• Early patient engagement in the design process is crucial for the success of new medical technologies in MS care.