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Regional assignment of human tissue factor gene (F3) to chromosome 1p21-p22
1Eleanor Roosevelt Institute for Cancer Research, Denver, Colorado 80206.
Somatic Cell and Molecular Genetics
|July 1, 1988
Abstract:
Tissue factor, or coagulation factor III, is a membrane-bound glycoprotein and acts as a cofactor for factor VII-dependent initiation of blood coagulation. The tissue factor gene (F3) was previously assigned to human chromosome 1, region p21-pter. The present report has further refined the mapping position to 1p21-p22 using a cDNA probe for the tissue factor gene and in situ hybridization to metaphase chromosomes.