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Updated: Nov 5, 2025
Measurements of Physiological Stress Responses in C. Elegans
Published on: May 21, 2020
A cysteine-selective fluorescent probe for monitoring stress response cysteine fluctuations
Yang Yang1, Liangwei Zhang2, Xia Zhang2
1College of Environment and Chemical Engineering, Dalian University, Dalian 116622, China. dlyhy@dicp.ac.cn and CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China. liangweizhang@yic.ac.cn lxchen@yic.ac.cn.
Abstract:
Rare studies provided evidence for the real-time monitoring of stress response cysteine fluctuations. Here, we have successfully designed and synthesized a cysteine-selective fluorescent probe 1 to monitor stress response Cys fluctuations, providing visual evidence of Hg2+ regulated cysteine fluctuations for the first time, which may open a new way to help researchers to reveal the mechanism of heavy metal ion poisoning.
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