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Published on: April 10, 2021
Amaranth leaf extract protects against hydrogen peroxide induced oxidative stress in Drosophila melanogaster
Ndinawe Johnmark1, Hellen W Kinyi2
1School of Pharmacy, Kampala International University, Kampala, Uganda.
Objective:
Amaranths leaves are rich in ascorbic acid and polyphenol compounds which have antioxidant activity. The aim of this study was to evaluate their in vivo antioxidant activity. The effect of consumption of Amaranth leaf extract on in vivo antioxidant activity, catalase enzyme activity and H2O2 induced oxidative stress in Drosophila melanogaster flies was assessed.
Results:
Consumption of Amaranth leaf extract was associated with increased survival on exposure to H2o2 in a dose dependent manner in Drosophila melanogaster flies. The study concludes that the ethanolic extract of Amaranth leaves offer protection against hydrogen peroxide-induced oxidative stress.

