Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Accessory Structures of the Skin: Nails01:05

Accessory Structures of the Skin: Nails

2.8K
Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
2.8K
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

79
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
79
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

238
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
238
Assessment of the Cardiovascular System II: Inspection01:29

Assessment of the Cardiovascular System II: Inspection

577
Inspection is the initial step in assessing the cardiovascular system. It involves a detailed visual examination that provides crucial information about a patient's circulatory and cardiac health. This systematic process, conducted from head to toe, helps identify signs of cardiovascular conditions by observing physical appearance, skin and mucous membranes, jugular and carotid pulsations, chest symmetry, and the condition of the extremities.
Head and Neck
577
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

52
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
52
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

96
Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
96

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Environmental criteria in dermatology research grants.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

What can dermatologists do about climate change? Introducing EADV Climate Task Force.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

Nail unit squamous cell carcinoma: A multicenter, retrospective study of the clinical and morphologic characteristics of 261 patients.

Journal of the American Academy of Dermatology·2026
Same author

Conceptual approaches to guideline-relevant carbon footprint evaluation in dermatological treatments.

The British journal of dermatology·2026
Same author

Armadillo nail.

The British journal of dermatology·2025
Same author

A retrospective observational study of effectiveness of sequential biologic and targeted synthetic DMARDs in psoriatic arthritis in the UK.

Rheumatology (Oxford, England)·2025
Same journal

Letter to the Editor: 'Life expectancy of UK physicians in the early 21st century: An analysis of 1,000 fellows from the Royal College of Physicians' Munk's Roll'.

Clinical medicine (London, England)·2026
Same journal

Finerenone Exposure and Ischemic Stroke in Patients with Type 2 Diabetes and Chronic Kidney Disease: A Propensity Score-Matched Cohort Study.

Clinical medicine (London, England)·2026
Same journal

Prevalence and predictive factors of chronic kidney disease among individuals with cardiometabolic risk factors: A multicenter cross sectional study, North East Ethiopia.

Clinical medicine (London, England)·2026
Same journal

Authors' response to Dr Lucy Williams' letter to the Editor: 'Life expectancy of UK physicians in the early 21st century: An analysis of 1,000 fellows from the Royal College of Physicians' Munk's Roll'.

Clinical medicine (London, England)·2026
Same journal

Resident doctor workforce wellbeing worldwide: lessons between the United Kingdom and Australia.

Clinical medicine (London, England)·2026
Same journal

Premature ventricular complexes.

Clinical medicine (London, England)·2026
See all related articles

Related Experiment Video

Updated: Nov 5, 2025

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy
05:06

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy

Published on: February 28, 2025

549

Nails in systemic disease.

Charlotte E Gollins1, David de Berker2

  • 1University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.

Clinical Medicine (London, England)
|May 18, 2021
PubMed
Summary
This summary is machine-generated.

Nail changes like alterations in color, size, shape, or texture can signal underlying systemic diseases. Recognizing these nail signs aids in diagnosing and managing patients with general medical conditions.

Keywords:
Beau'sclubbingkoilonychiamatrixnail

More Related Videos

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

320
Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
05:26

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients

Published on: March 1, 2024

1.5K

Related Experiment Videos

Last Updated: Nov 5, 2025

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy
05:06

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy

Published on: February 28, 2025

549
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

320
Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
05:26

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients

Published on: March 1, 2024

1.5K

Area of Science:

  • Dermatology
  • Internal Medicine
  • Oncology

Background:

  • Nails serve as a window to a patient's overall health.
  • Changes in nail appearance can be early indicators of systemic conditions.

Purpose of the Study:

  • To review common and rare nail changes associated with systemic diseases.
  • To highlight the diagnostic and management utility of nail examination in general medicine.

Main Methods:

  • Literature review of common and rare nail changes.
  • Correlation of nail findings with specific systemic diseases.
  • Clinical case examples illustrating diagnostic value.

Main Results:

  • Specific nail alterations are linked to various systemic diseases including cardiovascular, pulmonary, renal, and autoimmune conditions.
  • Rare nail changes can indicate less common but serious underlying pathologies.
  • Nail examination can provide crucial diagnostic clues.

Conclusions:

  • Systematic examination of fingernails and toenails is essential in clinical practice.
  • Nail changes offer valuable insights for diagnosing and managing systemic diseases.
  • Further research into specific nail-disease correlations is warranted.