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Crystal Growth: Principles of Crystallization

Crystal Growth: Principles of Crystallization

Crystallization is a phase transformation process in which crystals are precipitated from a supersaturated solution or formed from other sources. During crystallization, atoms or molecules arrange themselves into a well-defined, rigid crystal lattice to minimize energy.
Initiating crystallization involves manipulating the concentration of the solute and the temperature of the solution. Since crystal growth occurs when the ratio of concentration and solubility of the solute in the solvent...

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Updated: Nov 5, 2025

A Microfluidic Approach for the Study of Ice and Clathrate Hydrate Crystallization

A Microfluidic Approach for the Study of Ice and Clathrate Hydrate Crystallization

Published on: August 18, 2022

Microfluidic formation of crystal-like structures.

Francesco Del Giudice¹, Gaetano D'Avino², Pier Luca Maffettone²

¹System and Process Engineering Centre, College of Engineering, Fabian Way, Swansea, SA1 8EN, UK. francesco.delgiudice@swansea.ac.uk.

|May 18, 2021

Summary

This summary is machine-generated.

Microfluidic devices enable precise manipulation of droplets and particles to create crystal-like structures. Hydrodynamic interactions within these devices are key to forming these structures for various applications.

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$Microfluidic Chips for In Situ Crystal X-ray Diffraction and In Situ Dynamic Light Scattering for Serial Crystallography$

Microfluidic Chips for In Situ Crystal X-ray Diffraction and In Situ Dynamic Light Scattering for Serial Crystallography

Published on: April 24, 2018

Area of Science:

Biomedical engineering
Material science
Fluid dynamics

Background:

Crystal-like structures, including droplet and particle crystals, are vital in fields like high-throughput assays, material synthesis, and single-cell analysis.
Precise manipulation of micrometer-sized objects is essential for forming these crystal structures.
Microfluidic devices provide advanced tools for controlling droplets and particles.

Purpose of the Study:

To offer a comprehensive overview of crystal-like structure formation driven by hydrodynamic interactions in microfluidic systems.
To explore the physical basis of these hydrodynamic interactions.
To examine the influence of device geometry, fluid properties, and flow conditions on structure formation.

Main Methods:

Review of microfluidic techniques for manipulating droplets and particles.
Analysis of hydrodynamic interactions governing crystal formation.
Discussion of factors influencing microscale structure assembly.

Main Results:

Microfluidic devices facilitate the controlled assembly of crystal-like structures through hydrodynamic forces.
Hydrodynamic interactions are tunable by adjusting device design, fluid characteristics, and flow rates.
This manipulation enables diverse applications in material science and biomedical engineering.

Conclusions:

Hydrodynamically mediated crystal-like structure formation in microfluidics is a versatile fabrication method.
Understanding these interactions is crucial for optimizing crystal formation for specific applications.
Microfluidics offers a powerful platform for advanced material and biological applications.