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Cancer Therapies02:49

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Updated: Nov 5, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
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Radiotherapy for benign disorders: current use in clinical practice.

B Fionda1, V Lancellotta, C Casà

  • 1U.O.C. Radioterapia Oncologica, Dipartimento di Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. calogero.casa@guest.policlinicogemelli.it.

European Review for Medical and Pharmacological Sciences
|May 18, 2021
PubMed
Summary
This summary is machine-generated.

Radiation Therapy (RT) offers a viable treatment for various benign disorders when other medical options fail, potentially avoiding major surgery. Careful patient selection and discussion are crucial for successful outcomes.

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Area of Science:

  • Radiation Oncology
  • Non-oncological applications of RT

Background:

  • Radiation Therapy (RT) is primarily known for cancer treatment.
  • Its application in benign conditions remains less explored.

Purpose of the Study:

  • To update the clinical indications of RT for benign disorders.
  • To explore RT's role outside traditional oncological settings.

Main Methods:

  • Comprehensive literature search of PubMed, Scopus, and Cochrane databases up to December 2020.
  • Inclusion of English-language essays and manual checks of conference proceedings and books.
  • Keywords: "Radiotherapy" OR "Radiation Therapy" AND "Benign disorder" OR "Benign disease".

Main Results:

  • Identified current clinical indications for benign disorders across multiple sites.
  • Key areas include eye, bone, head and neck, skin, brain, heart, and peripheral vascular system.
  • RT is a feasible strategy for specific benign conditions.

Conclusions:

  • RT is a viable therapeutic option for debilitating benign conditions, particularly when medical therapies are ineffective.
  • It can serve as an alternative to major surgery.
  • Careful patient selection and thorough discussion of treatment choices are essential.