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Radiotherapy for benign disorders: current use in clinical practice.
B Fionda1, V Lancellotta, C Casà
1U.O.C. Radioterapia Oncologica, Dipartimento di Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. calogero.casa@guest.policlinicogemelli.it.
Summary
Radiation Therapy (RT) offers a viable treatment for various benign disorders when other medical options fail, potentially avoiding major surgery. Careful patient selection and discussion are crucial for successful outcomes.
Area of Science:
- Radiation Oncology
- Non-oncological applications of RT
Background:
- Radiation Therapy (RT) is primarily known for cancer treatment.
- Its application in benign conditions remains less explored.
Purpose of the Study:
- To update the clinical indications of RT for benign disorders.
- To explore RT's role outside traditional oncological settings.
Main Methods:
- Comprehensive literature search of PubMed, Scopus, and Cochrane databases up to December 2020.
- Inclusion of English-language essays and manual checks of conference proceedings and books.
- Keywords: "Radiotherapy" OR "Radiation Therapy" AND "Benign disorder" OR "Benign disease".
Main Results:
- Identified current clinical indications for benign disorders across multiple sites.
- Key areas include eye, bone, head and neck, skin, brain, heart, and peripheral vascular system.
- RT is a feasible strategy for specific benign conditions.
Conclusions:
- RT is a viable therapeutic option for debilitating benign conditions, particularly when medical therapies are ineffective.
- It can serve as an alternative to major surgery.
- Careful patient selection and thorough discussion of treatment choices are essential.
