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[Animal experiment studies of morphologic changes in the trachea and lung in high frequency ventilation]
H Eckert1, E Danzmann, H Voigt
1Forschungsinstitut für Lungenkrankheiten und Tuberkulose, Berlin-Buch/DDR.
Zeitschrift Fur Erkrankungen Der Atmungsorgane
|January 1, 1988
Abstract:
Prolonged high frequency ventilation (24 hrs) in dogs leads to morphological changes in the trachea as well as in the bronchi. Erosive changes of tracheal epithelium were observed whereas small bronchi and bronchioli exhibited luminal obstructions by mucus plugs, caused by hypersecretion of goblet cells. Using histochemical methods degenerative changes of bronchiolar epithelium were observed.