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Updated: Nov 5, 2025

Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research
Published on: June 8, 2017
[Neonatal hearing screening]
Françoise Denoyelle1, Isabelle Rouillon1, Fiona Alvin1
1Service d'oto-rhino-laryngologie et de chirurgie cervico-faciale, Hôpital Necker-Enfants malades, 149 rue de Sèvres, 75015 Paris, France.
Insights
Nationwide neonatal hearing screening programs are essential due to the high prevalence of hearing loss in infants. Early detection through Otoacoustic Emission and Auditory Evoked Potential testing improves treatment outcomes.
Area of Science:
- Pediatrics
- Audiology
- Public Health
Background:
- Neonatal hearing impairment affects approximately 1 in 1,000 infants.
- Delayed diagnosis, often after 18 months, reduces treatment efficacy.
- Effective screening tools like Otoacoustic Emission and Auditory Evoked Potential are available.
Purpose of the Study:
- To outline the rationale and organization of a nationwide neonatal hearing screening program.
- To highlight the importance of early detection for improved infant hearing outcomes.
Main Methods:
- Implementing regionalized screening programs.
- Training midwives and nurses to conduct hearing tests and counsel parents.
- Establishing referral pathways to specialized pediatric departments for diagnosis and treatment.
Main Results:
- The development of nationwide neonatal hearing screening programs is supported by strong evidence.
- Regional organization in France involves trained healthcare professionals and specialized follow-up.
Conclusions:
- Robust nationwide neonatal hearing screening is crucial for early identification of hearing impairment.
- Effective program organization, including professional training and referral systems, is key to successful implementation and improved infant health.
Abstract:
Neonatal hearing screening has been developped in a large number of countries. The rational to build such nationwide programs is robust. The prevalence of hearing impairment of various etiologies is high (1/1,000), diagnosis of hearing impairment in infants is uneasy and is made most of the time after the age of 18 months when treatment is less efficient and, last, appropriate test to screen for hearing impairment are available: Otoacoustic Emission and Auditory Evoked Potential. In France the screening is organised at the regional level. The organization of such a program is complexe. Midwifes and nurses should be trained to informed the parents and to perform the test. If the test is abnormal the infant will be oriented to a specialzed department of pediatrics for appropriate diagnosis and treatment.
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