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Intraoperative Retinal Changes May Predict Surgical Outcomes After Epiretinal Membrane Peeling.

Lekha K Mukkamala1, Jaycob Avaylon2, R Joel Welch1

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Intraoperative retinal thickness changes during epiretinal membrane (ERM) peeling surgery can predict surgical outcomes. Greater changes in intraoperative central macular thickness (iCMT) correlate with better anatomic and visual results after ERM removal.

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Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Medical Imaging

Background:

  • Epiretinal membrane (ERM) is a common cause of visual impairment.
  • Pars plana vitrectomy with membrane peeling is the standard surgical treatment for ERM.
  • Predicting surgical outcomes is crucial for patient management.

Purpose of the Study:

  • To determine if intraoperative retinal changes during ERM peeling affect surgical outcomes.
  • To investigate the correlation between intraoperative central macular thickness (iCMT) changes and postoperative results.

Main Methods:

  • Intraoperative optical coherence tomography (iOCT) was used to measure retinal thickness during ERM peeling.
  • Changes in iCMT were compared with postoperative central macular thickness (CMT) and best-corrected visual acuity (VA).
  • Twenty-seven eyes from patients undergoing ERM surgery were analyzed.

Main Results:

  • A mean intraoperative thinning of 39.6 µm was observed.
  • Greater absolute iCMT changes were associated with significant CMT reduction postoperatively.
  • Greater intraoperative thinning showed a trend towards better VA outcomes at 1 and 3 months.

Conclusions:

  • Intraoperative retinal thickness changes during ERM peeling may predict anatomic and visual outcomes.
  • iOCT measurements can serve as a prognostic indicator for retinal architecture restoration and visual acuity.