Related Experiment Video
Updated: Nov 5, 2025
10:34
Ligand Nano-cluster Arrays in a Supported Lipid Bilayer
Published on: April 23, 2017
7.1K
Granular chains with fixed side decoration as impact protector and signals filter
Luís Paulo Silveira Machado1, Surajit Sen2
1Universidade Federal do Pará, Campus Universitário de Tucuruí, Tucuruí-PA 68.464-000, Brazil.
Physical Review. E
|May 19, 2021
Summary
A novel granular architecture effectively protects against impacts and filters signals. This scalable system, using five granules, can attenuate over 90% of solitary pulse momentum, acting as a universal filter.
Area of Science:
- Physics
- Materials Science
- Mechanical Engineering
Background:
- Granular chains are explored for their unique dynamic properties.
- Impact protection and signal filtering are critical in various engineering applications.
- Existing granular systems have limitations in broad-spectrum signal attenuation.
Purpose of the Study:
- To design and evaluate a granular architecture for impact protection and signal filtering.
- To investigate the attenuation capabilities of decorated granular chains for solitary pulses.
- To characterize the filtering behavior of granular chains for sinusoidal signals.
Main Methods:
- Numerical simulations of monodispersed and tapered granular chains.
- Design of a granular system with side beads fixed on sidewalls.
- Analysis of momentum amplitude attenuation for solitary pulses.
- Investigation of low-pass filtering characteristics for sinusoidal signals.
Main Results:
- A five-axial-granule system with optimal design attenuates over 90% of solitary pulse momentum.
- Monodispersed and tapered granular chains act as low-pass filters with frequency dependent on signal parameters.
- The decorated granular chain with fixed side beads demonstrates universal filtering of all input signals.
Conclusions:
- The proposed granular architecture offers efficient impact protection and broadband signal filtering.
- Optimal design parameters, including material and granule size ratio, are crucial for performance.
- Decorated granular chains present a scalable and effective solution for complex signal manipulation.
Related Concept Videos
01:30Assembly of Signaling Complexes
6.1K
Multiprotein signaling complexes are formed in a dynamic process involving protein-protein interactions at the cytoplasmic domain of transmembrane receptors or enzymatic and non-enzymatic proteins associated with the receptor. These complexes ensure the activation and propagation of intracellular signals that regulate cell functions.
Interaction domains in cell signaling
Interaction domains recognize exposed features of their binding partners containing post-translationally modified sequences,...
Interaction domains in cell signaling
Interaction domains recognize exposed features of their binding partners containing post-translationally modified sequences,...
6.1K
01:41Signal Sequences and Sorting Receptors
11.9K
Signal sequences are short amino acid sequences that guide newly synthesized proteins to their proper location within the cell. Classical signal sequences are fifteen to sixty amino acids long and present at the N-terminus of a polypeptide chain. Each signal sequence has a conserved segment of basic residues towards their N terminus, a hydrophobic core, and a C-terminus rich in polar residues. The C-terminus also contains a signal cleavage site and features a -3 -1 sequence motif. The -3-1...
11.9K
01:12Golgi Matrix Proteins
2.2K
Golgi matrix proteins are a group of highly dynamic proteins that maintain the stacked structure of Golgi. These proteins adapt to rapid morphological changes of the Golgi during the cell cycle. During cell division, mild proteolysis removes these connections resulting in Golgi unstacking. In The daughter cells, these proteins help reassemble the unstacked Golgi.
One of the first identified Golgi matrix proteins was GM130, a rod-like protein located in the cis-Golgi. Subsequently, many Golgi...
One of the first identified Golgi matrix proteins was GM130, a rod-like protein located in the cis-Golgi. Subsequently, many Golgi...
2.2K
01:32Lipids as Anchors
6.6K
In the plasma membrane, the lipids forming the bilayer can also act as an anchor to tether proteins to the membrane. The three main types of lipid anchors found in eukaryotes are – prenyl groups, fatty acyl groups, and glycosylphosphatidylinositol or GPI groups. Prenyl and fatty acyl groups act as anchors on the cytosolic surface of the membrane, whereas GPI anchors proteins on the extracellular side.
The carboxy-terminal of most of the prenylated proteins, such as Ras proteins, contains...
The carboxy-terminal of most of the prenylated proteins, such as Ras proteins, contains...
6.6K
01:17Intracellular Signaling Affects Focal Adhesions
3.1K
Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
Some...
Some...
3.1K