First hitting times between a run-and-tumble particle and a stochastically gated target

We study the statistics of the first hitting time between a one-dimensional run-and-tumble particle and a target site that switches intermittently between visible and invisible phases. The two-state dynamics of the target is independent of the motion of the particle, which can be absorbed by the target only in its visible phase. We obtain the mean first hitting time when the motion takes place in a finite domain with reflecting boundaries. Considering the turning rate of the particle as a tuning parameter, we find that ballistic motion represents the best strategy to minimize the mean first hitting time. However, the relative fluctuations of the first hitting time are large and exhibit nonmonotonous behaviors with respect to the turning rate or the target transition rates. Paradoxically, these fluctuations can be the largest for targets that are visible most of the time, and not for those that are mostly invisible or rapidly transiting between the two states. On the infinite line, the classical asymptotic behavior ∝t^{-3/2} of the first hitting time distribution is typically preceded, due to target intermittency, by an intermediate scaling regime varying as t^{-1/2}. The extent of this transient regime becomes very long when the target is most of the time invisible, especially at low turning rates. In both finite and infinite geometries, we draw analogies with partial absorption problems.