Aseptic Viral Meningitis Secondary to Herpes Simplex Virus 2 Genital Infection

Camille Marshall1, Zachary T Clark2, Michael R Minckler3

  • 1Biology, Whitman College, Walla Walla, USA.

Cureus
|May 19, 2021
PubMed

Insights

Aseptic viral meningitis, often caused by herpes simplex virus type 2 (HSV-2), is common in the US. This case highlights HSV-2 meningitis in an untreated, immunosuppressed woman with genital herpes.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Virology

Background:

  • Aseptic viral meningitis is a frequent cause of meningitis in the United States.
  • Herpes simplex virus type 2 (HSV-2) is the predominant cause of herpes simplex virus meningitis.
  • Herpes simplex virus type 1 (HSV-1) is typically associated with viral encephalitis.

Observation:

  • This report details a case of aseptic meningitis.
  • The meningitis was caused by the herpes simplex virus type 2 (HSV-2).
  • The patient was a 35-year-old immunocompromised female with a recent diagnosis of untreated genital herpes due to medication side effects.

Findings:

  • Herpes simplex virus type 2 (HSV-2) can cause aseptic meningitis, particularly in immunosuppressed individuals.
  • Untreated genital herpes may pose a risk for developing HSV-2 meningitis.
  • This case underscores the importance of managing herpes simplex virus infections in immunocompromised patients.

Implications:

  • Highlights a potential complication of untreated genital herpes in an immunosuppressed population.
  • Emphasizes the need for vigilance in diagnosing and managing HSV-2 meningitis.
  • Informs clinical practice regarding herpes simplex virus management in vulnerable patient groups.