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Worldwide Early Impact of COVID-19 on Dialysis Patients and Staff and Lessons Learned: A DOPPS Roundtable Discussion
Bruce M Robinson1, Murilo Guedes2, Mohammed Alghonaim3,4
1Arbor Research Collaborative for Health, Ann Arbor, MI.
Insights
The COVID-19 pandemic disproportionately impacted dialysis patients globally, with over 100-fold variation in cases and deaths across countries. Dialysis patient outcomes remain severe, highlighting the need for improved pandemic preparedness in kidney care.
Area of Science:
- Nephrology
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic has severely affected maintenance dialysis patients and healthcare providers worldwide.
- Dialysis patients represent a vulnerable population with increased risk during global health crises.
Purpose of the Study:
- To compare the effects of COVID-19 on dialysis care across 15 countries.
- To analyze international data on COVID-19 cases, deaths, and risk factors in dialysis patients.
Main Methods:
- A virtual roundtable discussion involving Dialysis Outcomes and Practice Patterns Study (DOPPS) investigators from Asia, Europe, and the Americas.
- Analysis of international data on COVID-19 incidence and mortality among dialysis patients.
Main Results:
- Significant international variation (over 100-fold) in per-population cases and deaths among dialysis patients.
- Case-fatality ratio for dialysis patients remains high at 10% to 30%.
- In-center dialysis patients experienced higher rates of COVID-19 compared to home dialysis patients.
Conclusions:
- The pandemic's impact on dialysis care varies greatly worldwide, necessitating tailored public health strategies.
- Urgent research is needed to understand and mitigate higher infection rates in in-center dialysis settings.
- Increased telemedicine adoption and enhanced emergency preparedness are crucial for protecting dialysis patients and staff in future pandemics.
Abstract:
As the worst global pandemic of the past century, coronavirus disease 2019 (COVID-19) has had a disproportionate effect on maintenance dialysis patients and their health care providers. At a virtual roundtable on June 12, 2020, Dialysis Outcomes and Practice Patterns Study (DOPPS) investigators from 15 countries in Asia, Europe, and the Americas described and compared the effects of COVID-19 on dialysis care, with recent updates added. Most striking is the huge difference in risk to dialysis patients and staff across the world. Per-population cases and deaths among dialysis patients vary more than 100-fold across participating countries, mirroring burden in the general population. International data indicate that the case-fatality ratio remains at 10% to 30% among dialysis patients, confirming the gravity of infection, and that cases are much more common among in-center than home dialysis patients. This latter finding merits urgent study because in-center patients often have greater community exposure, and in-center transmission may be uncommon under optimal protocols. Greater telemedicine use is a welcome change here to stay, and our community needs to improve emergency planning and protect dialysis staff from the next pandemic. Finally, the pandemic's challenges have prompted widespread partnering and innovation in kidney care and research that must be sustained after this global health crisis.
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