Eating disorders are associated with adverse obstetric and perinatal outcomes: a systematic review

Maila de C das Neves1,2,3,4, Ananda A Teixeira3, Flávia M Garcia3

  • 1Comissão de Estudos e Pesquisa da Saúde Mental da Mulher, Associação Brasileira de Psiquiatria, Rio de Janeiro, RJ, Brazil.

Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999)
|May 19, 2021
PubMed

Insights

Eating disorders (EDs) in pregnant women are linked to adverse obstetric and perinatal outcomes, including perinatal depression and complications like anemia. Healthcare providers should screen for EDs during pregnancy to improve maternal and infant health.

Area of Science:

  • Reproductive Medicine
  • Psychiatry
  • Perinatal Health

Background:

  • Eating disorders (EDs) represent a significant public health concern.
  • Maternal mental health during pregnancy is crucial for both mother and child well-being.
  • Limited systematic reviews exist on the specific obstetric and perinatal impacts of EDs.

Purpose of the Study:

  • To systematically review existing literature on obstetric and perinatal outcomes in women with eating disorders.
  • To examine the consequences of maternal eating disorders for offspring development.
  • To synthesize evidence on the association between eating disorders and pregnancy complications.

Main Methods:

  • Systematic review and meta-analysis adhering to PRISMA guidelines.
  • Searched PubMed, SciELO, and Cochrane databases for non-interventional studies (1980-2020).
  • Assessed risk of bias using the American Agency for Healthcare Research and Quality's Methods guide.

Main Results:

  • 30 studies included, revealing associations between EDs and perinatal depression.
  • Common obstetric outcomes included vomiting, hyperemesis, bleeding, and anemia.
  • Anorexia nervosa and bulimia nervosa linked to low birth weight; binge EDs associated with increased birth weight.

Conclusions:

  • Eating disorders, particularly severe or acute cases, correlate with poor perinatal, obstetric, and neonatal outcomes.
  • Evidence highlights the need for increased vigilance among healthcare providers.
  • Obstetricians and general practitioners should proactively screen pregnant women for eating disorders.
Abstract

Related Concept Videos

Anorexia Nervosa01:28

Anorexia Nervosa

Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
335
Bulimia Nervosa01:30

Bulimia Nervosa

Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
294
Binge Eating Disorders01:23

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
236
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
2.3K
Oogenesis02:07

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
67.3K
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
3.2K