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Updated: Nov 5, 2025

A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis
Published on: May 10, 2022
Eating disorders are associated with adverse obstetric and perinatal outcomes: a systematic review
Maila de C das Neves1,2,3,4, Ananda A Teixeira3, Flávia M Garcia3
1Comissão de Estudos e Pesquisa da Saúde Mental da Mulher, Associação Brasileira de Psiquiatria, Rio de Janeiro, RJ, Brazil.
Insights
Eating disorders (EDs) in pregnant women are linked to adverse obstetric and perinatal outcomes, including perinatal depression and complications like anemia. Healthcare providers should screen for EDs during pregnancy to improve maternal and infant health.
Area of Science:
- Reproductive Medicine
- Psychiatry
- Perinatal Health
Background:
- Eating disorders (EDs) represent a significant public health concern.
- Maternal mental health during pregnancy is crucial for both mother and child well-being.
- Limited systematic reviews exist on the specific obstetric and perinatal impacts of EDs.
Purpose of the Study:
- To systematically review existing literature on obstetric and perinatal outcomes in women with eating disorders.
- To examine the consequences of maternal eating disorders for offspring development.
- To synthesize evidence on the association between eating disorders and pregnancy complications.
Main Methods:
- Systematic review and meta-analysis adhering to PRISMA guidelines.
- Searched PubMed, SciELO, and Cochrane databases for non-interventional studies (1980-2020).
- Assessed risk of bias using the American Agency for Healthcare Research and Quality's Methods guide.
Main Results:
- 30 studies included, revealing associations between EDs and perinatal depression.
- Common obstetric outcomes included vomiting, hyperemesis, bleeding, and anemia.
- Anorexia nervosa and bulimia nervosa linked to low birth weight; binge EDs associated with increased birth weight.
Conclusions:
- Eating disorders, particularly severe or acute cases, correlate with poor perinatal, obstetric, and neonatal outcomes.
- Evidence highlights the need for increased vigilance among healthcare providers.
- Obstetricians and general practitioners should proactively screen pregnant women for eating disorders.
Objective:
To systematically review the literature focusing on obstetric and perinatal outcomes in women with previous or current eating disorders (EDs) and on the consequences of maternal EDs for the offspring.
Methods:
The study was performed following the systematic review and meta-analysis (PRISMA) statement. PubMed, SciELO, and Cochrane databases were searched for non-interventional studies published in English or Portuguese from January 1980 to December 2020. Risk of bias was assessed using the Methods guide for effectiveness and comparative effectiveness reviews (American Agency for Healthcare Research and Quality).
Results:
The search yielded 441 records, and 30 articles were included. The psychiatric outcome associated with EDs in women was mainly perinatal depression. The most prevalent obstetric outcomes observed in women with EDs were vomiting, hyperemesis, bleeding, and anemia. Most studies found maternal anorexia nervosa and bulimia nervosa to be associated with low birth weight and slow fetal growth. Women with binge EDs delivered children with increased birth weight. Of the 30 studies included, methodological quality was good in seven, fair in eight, and poor in 15 studies.
Conclusion:
A considerable body of evidence was reviewed to assess obstetric and perinatal outcomes in EDs. Acute and lifetime EDs, especially if severe, correlated with poor perinatal, obstetric, and neonatal outcomes. Obstetricians and general practitioners should be vigilant and screen for EDs during pregnancy.
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