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Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
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The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
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Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
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Supporting the Patient on LSD Day.

Betsy Todd

    The American Journal of Nursing
    |May 19, 2021
    PubMed
    Summary

    This 1964 article explores the therapeutic use of lysergic acid diethylamide (LSD) in psychiatric settings, highlighting its benefits for alcoholism and the nurse

    Area of Science:

    • Psychiatric Nursing
    • History of Medicine
    • Psychoactive Substance Therapy

    Background:

    • Nursing curricula often omit historical context, despite its value.
    • The 1960s saw research into the therapeutic potential of lysergic acid diethylamide (LSD).
    • This article revisits a 1964 piece by nurse Kay Parley on LSD therapy.

    Observation:

    • Parley documented the positive effects of LSD therapy for alcoholism in a psychiatric research hospital.
    • The article emphasizes the enriching experience for nurses guiding patients through LSD treatment.
    • Parley's personal history of "manic-depressive psychosis" and LSD treatment informed her perspective.

    Findings:

    • LSD therapy demonstrated benefits for patients suffering from alcoholism.

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  • The nurse's role in facilitating LSD therapy was described as highly valued and impactful.
  • The historical account provides insight into early psychoactive substance research in psychiatry.
  • Implications:

    • There is a contemporary resurgence in interest regarding the therapeutic applications of psychedelic substances.
    • Understanding historical nursing practices with LSD offers context for current psychedelic-assisted therapy research.
    • Archived nursing literature provides valuable lessons for modern mental healthcare approaches.