Internet-Delivered Cognitive Behavior Therapy for Atopic Dermatitis: A Randomized Clinical Trial

Area of Science:

• Dermatology
• Psychiatry
• Digital Health

Background:

• Atopic dermatitis is a prevalent, chronic skin condition causing significant discomfort and inflammation.
• There is a need for accessible behavioral treatments for atopic dermatitis.
• Internet-delivered interventions offer a scalable solution to increase treatment accessibility.

Purpose of the Study:

• To evaluate the effectiveness of internet-delivered cognitive behavior therapy (CBT) for adults diagnosed with atopic dermatitis.
• To assess the scalability and resource requirements of this digital therapeutic approach.

Main Methods:

• A randomized clinical trial involving 102 adults with atopic dermatitis across Sweden.
• Participants were assigned to either 12 weeks of therapist-guided internet-delivered CBT or a control group receiving standard care instructions.
• Symptom reduction was measured using the Patient-Oriented Eczema Measure, with follow-up assessments up to 12 months.

Main Results:

• Internet-delivered CBT led to a significantly greater weekly reduction in atopic dermatitis symptoms compared to the control group (P < .001).
• The treatment demonstrated a moderate to large effect size (d = 0.75) and sustained benefits at 12-month follow-up.
• Significant improvements were also observed in itch intensity, perceived stress, sleep quality, and depression symptoms.

Conclusions:

• Internet-delivered CBT is an efficacious treatment for reducing atopic dermatitis symptoms.
• This digital therapy requires minimal therapist time, enhancing its potential for widespread accessibility.
• It represents a promising adjunct behavioral treatment for individuals with atopic dermatitis.