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[The biotransformation of fenetylline]
G Rücker1, M Neugebauer, P G Heiden
1Pharmazeutischen Institut, Universität Bonn.
Arzneimittel-Forschung
|April 1, 1988
Abstract:
After oral administration of 3,7-dihydro-1,3-dimethyl-7-2 [(1-methyl-2-phenylethyl)-amino-ethyl]-1H-purine-2,6-dione (fenetylline, Captagon), 7 new metabolites could be detected in urine besides 4 known substances. The metabolites were identified by gas chromatography (GC) and by comparison of the mass spectra (MS) of metabolites with those of authentic reference compounds using a combined GC/MS method.