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Brain fetal neuroradiology: a beginner's guide
Giulia Moltoni1, Giacomo Talenti2, Andrea Righini3
1Neuroradiology Unit, NESMOS (Neurosciences, Mental Health and Sensory Organs) Department, S. Andrea Hospital, University Sapienza, Rome, Italy.
Translational Pediatrics
|May 20, 2021
Summary
Fetal magnetic resonance imaging (MRI) enhances prenatal diagnosis of central nervous system (CNS) anomalies. This review guides trainees on using advanced MRI techniques for better fetal brain and spine anomaly detection.
Area of Science:
- Medical Imaging
- Prenatal Diagnosis
- Neuroscience
Background:
- Fetal magnetic resonance imaging (MRI) is increasingly vital for diagnosing central nervous system (CNS) anomalies.
- It serves as a third-level examination, often following expert neuro-ultrasonography (US) or known genetic disorders.
- MRI offers superior visualization of fetal brain structures compared to US, detecting anomalies missed by ultrasound.
Purpose of the Study:
- To provide a practical guide for trainees and fellows on fetal MRI.
- To cover indications, safety, and protocols for state-of-the-art fetal MRI sequences.
- To review normal fetal brain development and common CNS and spine abnormalities.
Main Methods:
- Review of current literature and clinical practices in fetal MRI.
- Discussion of advanced MRI technologies, including ultrafast sequences and 3T scanners.
- Integration of knowledge on normal fetal brain development and MR appearance.
Main Results:
- Fetal MRI provides detailed characterization of fetal brain structures, improving anomaly detection.
- Advanced MRI techniques minimize motion artifacts and enable sophisticated studies.
- Knowledge of normal development is crucial for identifying abnormalities.
Conclusions:
- Fetal MRI is a powerful tool for prenatal diagnosis of CNS anomalies, aiding in pregnancy management and counseling.
- Trainees benefit from understanding MRI protocols, safety, and interpretation of fetal neuroimaging.
- Accurate diagnosis relies on expertise in fetal neuroanatomy and pathology via MRI.

