Cystic fibrosis: A changing landscape
Camille Wendekier1, Katheryn Wendekier-Raybuck
1Camille Wendekier is program director, leadership/education at Saint Francis University in Loretto, Pa., and Katheryn Wendekier-Raybuck is a pharmacist in Pittsburgh, Pa.
Abstract:
Cystic fibrosis (CF) is an autosomal recessive genetic disorder that causes a lifetime of debilitating and life-threatening complications affecting the lungs and other organ systems. Over 1,700 gene mutations that cause this rare disorder have been identified. This article describes the current treatment landscape for adults with CF, including the 2019 FDA approval of a breakthrough triple-drug combination therapy that may significantly improve the quality of life for an estimated 90% of patients with CF.
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