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Pigmentation01:19

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
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Bilateral idiopathic choroidal hyperpigmentation.

Ramesh Venkatesh1, NikithaGurram Reddy1, Jophy Philips Cherry1

  • 1Department of Retina and Vitreous, Narayana Nethralaya, Bengaluru, Karnataka.

European Journal of Ophthalmology
|May 21, 2021
PubMed
Summary
This summary is machine-generated.

Bilateral circumpapillary hyperpigmentation, a finding on routine fundus examination, was observed in three patients. This condition, suggestive of choroidal hypermelanosis, remained stable over years.

Keywords:
Circumpapillarybenignhyperpigmentationimagingmelanosisoptical coherence tomography

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Area of Science:

  • Ophthalmology
  • Retinal Imaging
  • Choroidal Diseases

Background:

  • Circumpapillary hyperpigmentation is a finding observed during routine fundus examinations.
  • Differential diagnosis for peripapillary pigmented lesions is crucial in ophthalmology.

Purpose of the Study:

  • To report a series of cases presenting with bilateral circumpapillary hyperpigmentation.
  • To describe the imaging characteristics and clinical course of this condition.

Main Methods:

  • Observational case series involving three patients.
  • Multimodal retinal imaging, including optical coherence tomography (OCT).
  • Clinical follow-up over 2-6 years.

Main Results:

  • Multimodal imaging revealed hyperpigmentation confined to the choroid.
  • OCT findings were suggestive of choroidal hypermelanosis.
  • No changes in visual acuity or lesion characteristics were observed during follow-up.

Conclusions:

  • Bilateral circumpapillary hyperpigmentation should be considered in the differential diagnosis of bilateral peripapillary pigmented lesions.
  • The condition appears to be benign and stable over time.